Adherence to guidelines and mortality in atrial fibrillation

Díez-Manglano, Jesús; Gomes-Martín, Javier; Al-Cheikh-Felices, P.; Pérez, S. Isasi de Isasmendi; Díez-Angulo, Raquel; Clemente-Sarasa, Carolina

doi:10.1016/j.ijcard.2014.07.098

Cited by 14 publications

(12 citation statements)

References 51 publications

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“…At admission, just 51.9% of the patients were treated. Similar data have been observed in various studies in Spain, 5,8 Europe, 13 North America 14 and Japan. 15 A recent study in southern China reported a use of OA of only 11.5%.…”

Section: Discussionsupporting

confidence: 91%

“…The use of oral anticoagulants (OA) decreases the onset of NVAF‐related embolic events. When the clinical practice guidelines are followed, survival is increased . However, OA are still underutilized.…”

Section: Introductionmentioning

confidence: 99%

“…When the clinical practice guidelines are followed, survival is increased. 8 However, OA are still underutilized. In actual practice, the use of OA in older patients with NVAF does not exceed 50%.…”

Section: Introductionmentioning

confidence: 99%

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Factors associated with discontinuing or not starting oral anticoagulant therapy in older hospitalized patients with non‐valvular atrial fibrillation

Díez-Manglano

Mostaza²,

Pose

et al. 2018

Geriatrics Gerontology Int

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

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Factors associated with discontinuing or not starting oral anticoagulant therapy in older hospitalized patients with non‐valvular atrial fibrillation

Díez-Manglano

Mostaza²,

Pose

et al. 2018

Geriatrics Gerontology Int

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“…Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is associated with significant morbidity and mortality . AF increases the risk of stroke, and several scoring systems have been developed to stratify the risk.…”

Section: Introductionmentioning

confidence: 99%

Hyperglycemia on admission and hospitalization outcomes in patients with atrial fibrillation

Akirov

Grossman

Shochat

et al. 2017

Clinical Cardiology

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Background We evaluated the association of admission blood glucose (ABG) and mortality in patients with and without diabetes mellitus (DM) hospitalized for atrial fibrillation (AF). Hypothesis Hyperglycemia on admission is a bad prognostic marker in patients with AF. Methods Observational data were collected from electronic records of patients age ≥ 18 years hospitalized for AF in 2011–2013. Twelve‐month data were available in all cases. ABG levels were classified as follows: 70 to 110 mg/dL, normal; 111 to 140 mg/dL, mildly elevated; 141 to 199 mg/dL, moderately elevated; ≥200 mg/dL, markedly elevated. Cox proportional hazards model was used to assess overall survival by ABG categories, adjusted for study variables. Primary outcome measure was mortality at end of follow‐up. Results The cohort included 1127 patients (45% male; median age, 75 ± 13 years), of whom 331 had DM. Mortality rates by ABG levels were 19% (77/407 patients), normal ABG; 26% (92/353 patients), mildly elevated ABG; 28% (69/244 patients), moderately elevated ABG; and 41% (50/123 patients), markedly elevated ABG. Data were analyzed for the entire cohort following adjustment for age, sex, CHADS2 score, ischemic heart disease, smoking, and alcohol consumption. Compared with normal ABG, the adjusted hazard ratio for mortality was higher in patients with moderately elevated ABG (2.1, 95% confidence interval: 1.19‐7.94, P < 0.05) and markedly elevated ABG (1.6, 95% confidence interval: 1.02‐5.31, P < 0.05). Conclusions In patients with and without DM hospitalized for AF, moderately to markedly elevated ABG levels are associated with increased mortality.

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“…Oral anticoagulation (OAC) in AF patients reduces the risk of stroke by 64% and the risk of all cause mortality by approximately 26% compared to control or placebo in trials 1 , with similar beneficial outcomes seen in everyday clinical practice [1][2][3][4][5] . For years, the Vitamin K Antagonists (VKAs, mainly warfarin and acenocoumarol) were the first option for OAC and thus, widely used worldwide.…”

Section: Introductionmentioning

confidence: 98%

Prediction of long-term net clinical outcomes using the TIMI-AF score: Comparison with CHA 2 DS 2 -VASc and HAS-BLED

Rivera‐Caravaca

Roldán

Esteve-Pastor

et al. 2018

American Heart Journal

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Adherence to guidelines and mortality in atrial fibrillation

Cited by 14 publications

References 51 publications

Factors associated with discontinuing or not starting oral anticoagulant therapy in older hospitalized patients with non‐valvular atrial fibrillation

Factors associated with discontinuing or not starting oral anticoagulant therapy in older hospitalized patients with non‐valvular atrial fibrillation

Hyperglycemia on admission and hospitalization outcomes in patients with atrial fibrillation

Prediction of long-term net clinical outcomes using the TIMI-AF score: Comparison with CHA 2 DS 2 -VASc and HAS-BLED

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