Adherence to Medication in Depressive Patients

Roca, Miquel; Armengol, S.; Salvador‐Carulla, Luis; Monzón, Saray; Salvà, Joan; Gili, Margalida

doi:10.1097/jcp.0b013e3182223af9

Cited by 18 publications

(29 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Low adherence to antidepressant medications and severity of depression had a negative correlation, with a significance at the P =0.01 level, which is compatible with results of Roca et al36 and Russell et al;37 however, other studies did not find a relationship between adherence and severity of depression 6. This finding can be explained by an inverse causal association, suggesting that adherence to a treatment regimen may lead to a better clinical outcome 20…”

Section: Discussionsupporting

confidence: 82%

Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study

Jumah¹,

Hassali²,

Qhatani³

et al. 2014

NDT

View full text Add to dashboard Cite

BackgroundSeveral studies have investigated the factors associated with adherence to antidepressants, with inconsistent conclusions. However, no similar study has investigated this issue among patients diagnosed with major depressive disorder in Saudi Arabia. The aim of this study is to explore patients’ adherence to antidepressant medications, and the factors associated with adherence.MethodsA non-experimental cross-sectional design was used to measure adherence to antidepressants among major depressive disorder patients, and the factors associated with adherence. The patients were recruited from the outpatient clinic at the Al-Amal Complex for Mental Health in Riyadh, Saudi Arabia, between August 2013 and January 2014. Eligible participants met with one of the research coordinators for assessment of their adherence. Adherence was investigated indirectly by use of the Morisky Medication Adherence Scale, and patients’ beliefs were assessed through the Beliefs about Medicine Questionnaire. Information about the severity of their depression, demographics, and other study variables were collected.ResultsA total of 403 patients met the inclusion criteria and participated in the study. Of those, 203 (50.37%) were females, while the remaining 200 (49.6%) were males. There was an average age of 39 years (standard deviation, ±11 years). Half of the patients (52.9%) reported low adherence to their antidepressant medication, with statistically significant differences between the low adherence and high adherence scores relating to sex, age, and duration of illness.ConclusionLow medication adherence is a common problem among major depressive disorder patients in Saudi Arabia. Medication-taking behavior among depressed patients is influenced by several factors, mainly patients’ beliefs regarding antidepressants. This study has improved the understanding of the factors associated with adherence to antidepressants.

show abstract

Section: Discussionsupporting

confidence: 82%

Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study

Jumah¹,

Hassali²,

Qhatani³

et al. 2014

NDT

View full text Add to dashboard Cite

show abstract

“…Twenty-three studies were performed in the United States,20–42 two in Canada,43,44 two in Spain,45,46 two in Taiwan,47,48 one in the United Kingdom,49 one in Belgium,17,18 and one in New Zealand 50. Sample sizes were less than 100 in eight studies, 100–600 in eleven studies, and more than 2000 in 12 studies.…”

Section: Resultsmentioning

confidence: 99%

Sociodemographic and clinical predictors of compliance with antidepressants for depressive disorders: systematic review of observational studies

Rivero‐Santana

Perestelo-Pérez²,

Pérez-Ramos³

et al. 2013

PPA

View full text Add to dashboard Cite

BackgroundThe literature shows that compliance with antidepressant treatment is unsatisfactory. Several personal and disease-related variables have been shown to be related to compliance behavior. The objective of this study was to review the literature about sociodemographic and clinical predictors of compliance in patients with depressive disorders.MethodsThe Medline, Embase, Cochrane Central, PsycInfo, and Cinahl databases were searched until May 2012. Studies that analyzed sociodemographic and clinical predictors or correlates of compliance in patients with depressive disorder were included. A quantitative synthesis was not performed because of the heterogeneity and availability of the data reported. For similar reasons, the results were not classified according to the different phases of treatment. The search was limited to studies published in English and Spanish.ResultsThirty-two studies fulfilled the inclusion criteria. The most consistent associations with compliance were found for age (older patients showed more compliance) and race (white patients were more likely to adhere to treatment than minority ethnic groups). Few studies assessed clinical factors, and the most plausible predictors of compliance were certain comorbidities and substance abuse. Severity of depression did not play an important role in predicting compliance.ConclusionThe impact of the variables studied on compliance behavior appeared to be inconsistent. Identifying potential predictors of compliance with antidepressant treatment is important, both for the routine practice of the mental health professional and for refining interventions to enhance adherence and target them to specific populations at risk of noncompliance.

show abstract

“…This is because we agree that mental health status and socioeconomic factors do not have separate and independent effects and, thus, mental health status can be understood as an intermediator [15]. According to recent studies [37,38,39], unemployment and low levels of income are important predictors of non-adherence to treatment medications among patients with mental disorders. As such, it shows a possible facet of the intermediate relationship between helplessness caused by unstable employment and subsequent impaired mental status.…”

Section: Discussionmentioning

confidence: 99%

Does Unstable Employment Have an Association with Suicide Rates among the Young?

Kim

Cho

2017

IJERPH

View full text Add to dashboard Cite

Although a growing body of literature has indicated that unemployment has a positive association with suicide, the dynamic aspects of unstable employment have not yet been considered in suicidology. This study explored the association between employment stability and completed suicide among people aged 25–34 years in 20 OECD (Organization for Economic Cooperation and Development) countries with time-series data (1994–2010). In order to consider the different aspects of unstable employment, we tested the impacts of employment protection legislation indicators as another proxy of job insecurity (employed, but unstable) apart from unemployment rates. Covariates, including economic growth rates, GDP per capita, fertility rates, and divorce rate, were controlled for. The analysis was designed to be gender- and age-specific, where observations with ages of 25–29 were separated from those with ages of 30–34. Random effect models were applied to examine changes over time in suicide rates, and other models were presented to check robustness. The results showed that it is a low level of employment protection, rather than unemployment itself, that was associated with increased suicide rates among all of the studied populations. The magnitude of the effect differed by gender.

show abstract

Adherence to Medication in Depressive Patients

Cited by 18 publications

References 12 publications

Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study

Factors associated with adherence to medication among depressed patients from Saudi Arabia: a cross-sectional study

Sociodemographic and clinical predictors of compliance with antidepressants for depressive disorders: systematic review of observational studies

Does Unstable Employment Have an Association with Suicide Rates among the Young?

Contact Info

Product

Resources

About