Adherence to medications and associated factors: A cross-sectional study among Palestinian hypertensive patients

Al-Ramahi, Rowa′

doi:10.1016/j.jegh.2014.05.005

Cited by 105 publications

(132 citation statements)

References 20 publications

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“…A study in north-west Ethiopia [37] also found that patients with no and one co-morbidity were more likely to adhere to their treatment than those with two (AOR = 2.50, 95% CI: 1.01 -6.21) or more than two co-morbidities (AOR = 2.68, 95% CI: 1.07 -6.71). However, having no other chronic disease ( = 0.009) was a significant factor influencing MNA among hypertensive patients in Palestine [38].…”

Section: Demographic Factorsmentioning

confidence: 87%

“…A study in Palestine found that patients with hypertension were not adhering to their medication due to the fear of dependent on medicines (AOR = 8.00; 95% CI: (2. 44 -26.19) [38]. Similarly avoiding side effects of drugs (AOR = 3.0; 95% CI: 1.4 -6.7) was an important reason for non-adherence to their treatment regimen among hypertensive patients in Nigeria [42].…”

Section: Perceptions Regarding Hypertension and Its Severitymentioning

confidence: 92%

“…Studies in Nigeria (OR = 14.8; 95% CI: 3.9 -54.8) [42] and Palestine (AOR = 5.12; 95% CI: 3.12 -8.41) [38] found significant correlation between forgetfulness and nonadherence among hypertensive patients.…”

Section: Mmas 4 Ethiopia; N = 384 Open Journal Of Epidemiologymentioning

confidence: 94%

“…Younger age was found to be significantly associated with MNA to hypertensive medications in India (≤57 years) [OR (odd ratio) 3.348; 95% Confidence Interval (CI): 1.665 -6.732] [27], Palestine (<45 years) (OR = 0.40; 95% CI: 0.157 -0.99) [38] and Pakistan (≤51 years) (OR = 1.0; 95% CI: 1.00 -1.04). The mean age of hypertensive patients who were not adherent to medications was 54.5 ± 13.2 years while those who were adherent had a mean age of 60.9 ± 12.1 years ( < 0.001) in Ghana and Nigeria [26].…”

Section: Demographic Factorsmentioning

confidence: 99%

See 3 more Smart Citations

A Systematic Review of Factors Influencing Medication Adherence to Hypertension Treatment in Developing Countries

Dhar¹,

Dantas²,

Ali³

2017

OJEpi

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Background: Coronary heart disease (CHD), a complication of hypertension, is one of the most important and common causes of morbidity, hospitalisation, and mortality among hypertensive population. In recent decades, increased urbanisation and changes to lifestyle, diet and physical activity in developing countries have led to a major increase in the population incidence of chronic diseases including CHD. Poor medication adherence is one of the leading causes of failure to achieve hypertension control. The objective of this systematic review is to describe the prevalence of non-adherence to antihypertensive medications among hypertensive population in developing countries and identify factors associated with it. Methods: A literature search was conducted using the following scholarly electronic databases: Proquest, PubMed, JSTOR and Science Direct. The online search engine, Google Scholar was also used to search for and identify relevant papers. Peer-reviewed fulltext articles published in English on hypertensive adults in developing countries that measured adherence to antihypertensive medications and their associations with different factors were eligible for inclusion. The review followed the PRISMA reporting and analytical guidelines for systematic reviews. Results: In all, 42 studies conducted across 19 developing countries were selected for the review. The mean prevalence of medication non-adherence (MNA) among the select hypertensive population was 47.34%. Very few studies were conducted in community settings and except for one, no study examined gender differences in MNA factors. The analysis revealed a range of factors that can influence MNA including low household income and socioeconomic status; knowledge and beliefs of hypertension and its management; avoiding side effects of medications; cost of medication; use of herbal preparations; absence of symptoms; irregular follow-up; and dissatisfaction with the treatment and health services provided. There was a general lack of consideration of role of health system in health care delivery, self-efficacy, cultural barriers, per- There was also a lack of gender-specific research which is necessary at community settings given the social and economic vulnerabilities faced by women in developing countries that may affect adherence to antihypertensive medications. Conclusions: Future research in developing countries should consider individual risk perceptions, cultural barriers, gender and the role of local health system in health care delivery when assessing MNA among hypertensive population at community settings.

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Section: Demographic Factorsmentioning

confidence: 87%

Section: Perceptions Regarding Hypertension and Its Severitymentioning

confidence: 92%

Section: Mmas 4 Ethiopia; N = 384 Open Journal Of Epidemiologymentioning

confidence: 94%

Section: Demographic Factorsmentioning

confidence: 99%

See 2 more Smart Citations

A Systematic Review of Factors Influencing Medication Adherence to Hypertension Treatment in Developing Countries

Dhar¹,

Dantas²,

Ali³

2017

OJEpi

View full text Add to dashboard Cite

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“…While oral agents pose many notable advantages when compared to conventional parenteral drugs, including enhanced convenience of self‐administration, reduced hospital and societal costs, and improved patient engagement in their own care 1, 2, 3, 4, these benefits must be balanced against growing concerns regarding poor compliance to treatment and its potentially negative impact on outcomes 1, 2, 3, 4, 5, 6. Suboptimal adherence to medications is a commonly recognized problem for many chronic medical conditions, such as hypertension and diabetes mellitus, where it has been shown to compromise drug effectiveness 7, 8, 9, 10.…”

Section: Introductionmentioning

confidence: 99%

Compliance with adjuvant capecitabine in patients with stage II and III colon cancer: comparison of administrative versus medical record data

et al. 2016

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We aimed to examine the frequency of treatment delays as well as the reasons and appropriateness of such delays in early stage colon cancer patients receiving adjuvant capecitabine by comparing data from pharmacy dispensing versus medical records. Patients diagnosed with stage II or III colon cancer from 2008 to 2012 and who received at least two cycle of adjuvant capecitabine were reviewed for treatment delays. Data from pharmacy dispensing and patient medical records were compared. Multivariate regression models were constructed to identify predictors of treatment delays. A total of 697 patients were analyzed: median age was 70 years (IQR 30–89), 394 (57%) were men, 598 (86%) reported Eastern Cooperative Oncology Group 0/1, and 191 (27%) had stage II disease. In this study cohort, 396 (57%) patients experienced at least 1 treatment delay during their adjuvant treatment. Upon medical record review, half of treatment delays identified using pharmacy administrative data were actually attributable to side effects, of which over 90% were considered clinically appropriate for patients to withhold rather than to continue the drug. The most prevalent side effects were hand‐foot syndrome and diarrhea which occurred in 176 (44%) and 67 (17%) patients, respectively. Multivariate analysis revealed a statistically significant association between stage and inappropriate treatment delays whereby patients with stage II disease were more likely to experience drug noncompliance (OR 1.79, 95% CI: 1.27–2.53, P < 0.001) than those with stage III disease. Compliance with adjuvant capecitabine was reasonable. Adherence ascertained from pharmacy administrative data differs significantly from that obtained from medical records.

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Perception of hypertension and adherence to hypertension treatment among patients attending a hospital in western Iran: A cross‐sectional study

Baharvand,

Malekshahi,

Babakhani

2023

Health Science Reports

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Background and AimsHypertension is the third leading cause of death in the world and is estimated to be increased by about 60% by 2025. Beliefs about hypertension can predict patient adherence to hypertension treatment. This study aims to investigate the perceptions of hypertension and adherence to hypertension treatment among patients in Khorramabad, Iran.MethodsThis is a descriptive/analytical study with a cross‐sectional design. Participants were 265 patients with a history of hypertension referred to a hospital in Khorramabad, Lorestan Province in western Iran in 2020, who were selected using a convenience sampling method. A demographic form, the brief illness perception questionnaire‐revised (BIPQ‐R), and Morisky medication adherence scale (MMAS‐8) were used for collecting data. The collected data were analyzed in SPSS v.22 software using descriptive statistics, Pearson's correlation test, independent t‐test, one‐way ANOVA, and regression analysis.ResultsThe mean scores of BIPQ‐R and MMAS‐8 were 49.05 ± 15.45 (out of 80) and 3.69 ± 1.62 (out of 8), respectively. There was a significant relationship between the mean scores of MMAS‐8 and BIPQ‐R in total (p < 0.001). Perceptions of illness consequences (B = 4.59, p = 0.005), personal control (B = 0.190, p = 0.047), and symptoms (B = 1.77, p = 0.005) could significantly predict treatment adherence of patients. In illness perception, there were significant differences among patients with different places of residence (p = 0.032), educational levels (p = 0.001), and employment status (p = 0.010). In treatment adherence, there were significant differences among patients with different places of residence (p = 0.042) and educational levels (p = 0.045).ConclusionTreatment adherence of hypertensive patients in western Iran is at a low level, while their perception of hypertension is at a moderate level. Clinical physicians are recommended to pay attention to the perception of illness in these patients (especially unemployed and less educated patients living in rural areas) to improve their adherence to treatment and blood pressure control.

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Adherence to medications and associated factors: A cross-sectional study among Palestinian hypertensive patients

Cited by 105 publications

References 20 publications

A Systematic Review of Factors Influencing Medication Adherence to Hypertension Treatment in Developing Countries

A Systematic Review of Factors Influencing Medication Adherence to Hypertension Treatment in Developing Countries

Compliance with adjuvant capecitabine in patients with stage II and III colon cancer: comparison of administrative versus medical record data

Perception of hypertension and adherence to hypertension treatment among patients attending a hospital in western Iran: A cross‐sectional study

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