Adherence to Recommendations of the Age-Related Eye Disease Study in Patients With Age-Related Macular Degeneration

Hochstetler, B. S.; Scott, Ingrid U.; Kunselman, Allen R.; Thompson, Kyle; Zerfoss, Erica

doi:10.1097/iae.0b013e3181cea5c6

Cited by 21 publications

(27 citation statements)

References 9 publications

(13 reference statements)

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“…The concordance rate in clinic 2 is in the same order of rates seen in the other AREDS compliance studies [10,11,12,19]. In clinic 1, the concordance rate is extraordinarily high when compared to concordance studies of AREDS recommendations and to long-term therapy commonly seen in medical practice [10,11,12,13,19,20]. This confirms the role of rigorous education in increasing the concordance rate.…”

Section: Discussionsupporting

confidence: 68%

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The Effect of Intensive Education on Concordance with the Age-Related Eye Disease Study (AREDS) Recommendations in a Tertiary Referral Practice

Weaver

Beaumont²

2014

Ophthalmologica

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Background/Aims: The Age-Related Eye Disease Study (AREDS) showed that supplementation with their formula led to a significant decrease in progression of age-related macular degeneration (AMD). This study aims to assess the effect of different education protocols on concordance with the trial recommendations in two retinal clinics. Methods: A prospective controlled survey of concordance with the AREDS recommendations in two retinal clinics was administered to 330 patients with AREDS category 3 or 4 AMD. The results were evaluated to assess the effect of differing levels of patient education. In clinic 1, there was a formal policy of giving the patient both verbal and written instructions and verbal repetition of these instructions from each staff member on each patient visit; in clinic 2, there was no specific education policy. Results: Clinic 1 had a concordance rate of 81.6% and clinic 2 of 44.1%. There were no significant differences in the patient demographics between the two clinics. Conclusion: A high concordance rate can be achieved in clinical practice with rigorous patient education that includes a policy of having continual repetition of instructions.

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Section: Discussionsupporting

confidence: 68%

“…In the literature the reported concordance rate with AREDS recommendations varies between 1 and 61% [10,11,12,13]. These studies have suggested that expense, size of tablets, polypharmacy and education are responsible for the variation.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Intensive Education on Concordance with the Age-Related Eye Disease Study (AREDS) Recommendations in a Tertiary Referral Practice

Weaver

Beaumont²

2014

Ophthalmologica

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“…We detected that almost 70% of our patients with late AMD were taking oral antioxidant supplements for AMD, although no benefit was anticipated by AREDS. Interestingly, a similar rate of use was also found in patients with AMD category 3 or 4 who were shown to benefit from the AREDS formula 8,9. AREDS also reported a 71% rate of adherence to their study tablets 6…”

Section: Discussionmentioning

confidence: 57%

Factors affecting the use of antioxidant supplements in patients with late AMD

Yu¹,

Paul²,

Schaumberger³

et al. 2014

OPTH

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BackgroundThe purpose of this study was to assess the use of oral antioxidant supplements in patients with late age-related macular degeneration (AMD) and to identify influencing factors that may affect the use of such supplements.MethodsThe study included 47 patients with late AMD. Using a questionnaire, the patients were asked for their demographic, ophthalmologic, and systemic data, their source of recommendation of antioxidant use for AMD, and/or their reasons for nonuse. The demographic, ophthalmologic, and systemic information was correlated with use or nonuse of oral antioxidant supplements for AMD.ResultsSixty-eight percent (32/47) of patients took antioxidant supplements for AMD and 32% (15/47) of patients did not. There were no statistically significant differences in demographic, ophthalmologic, and systemic parameters between patients with late AMD who used supplements and those who did not. Two thirds of patients with late AMD (66%, 31/47) reported being recommended oral antioxidant supplements for AMD by their ophthalmologist. Patients who did not use antioxidant supplements either did not obtain any recommendation or did not believe in their benefits.ConclusionThis study shows that most patients with late AMD use antioxidant supplements despite the recommendation to do so being missing in the Age-Related Eye Disease Study. Our study emphasizes the importance of seeking further therapeutic options for patients with late AMD.

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“…This phenomenon may be related to the fact that most patients were recommended AREDS supplementation by their ophthalmologists. So did Hochstetler et al 12 report that all patients who were using antioxidant supplements obtained their information about supplement use by their retina specialist. Similarly, in our study, the major source of recommendation for oral supplement use for AMD was the patients' ophthalmologist.…”

Section: Discussionmentioning

confidence: 97%

Factors Influencing Self-Reported Use of Antioxidant Supplements in Patients with Age-Related Macular Degeneration

Paul

Schaumberger

et al. 2014

Current Eye Research

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Adherence to Recommendations of the Age-Related Eye Disease Study in Patients With Age-Related Macular Degeneration

Abstract: Patients with intermediate or advanced AMD in at least one eye show a low adherence rate to the AREDS recommendations for vitamin supplementation.

Cited by 21 publications

References 9 publications

The Effect of Intensive Education on Concordance with the Age-Related Eye Disease Study (AREDS) Recommendations in a Tertiary Referral Practice

The Effect of Intensive Education on Concordance with the Age-Related Eye Disease Study (AREDS) Recommendations in a Tertiary Referral Practice

Factors affecting the use of antioxidant supplements in patients with late AMD

Factors Influencing Self-Reported Use of Antioxidant Supplements in Patients with Age-Related Macular Degeneration

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