Adherence to treatment of latent tuberculosis infection in a clinical population in New York City

Abstract

Shorter regimen and DOPT increased completion rates for LTBI. Though efforts to improve TLTBI completion need to address all groups, greater focus is needed for persons who are contacts and HIV-infected, as they have higher risk of developing TB.

Prevalence of latent tuberculosis and treatment adherence among patients with chronic kidney disease in Campo Grande, State of Mato Grosso do Sul

“…Treatment adherence in this study reached 97.7%, which was greater than the adherence rates reported in other studies (e.g., 87.7% and 44%) 47,48 .…”

Loss to follow up from isoniazid preventive therapy among adults attending HIV voluntary counseling and testing sites in Uganda

“…Alternatively, since the majority of Ugandan youth are unemployed, 17 their less stable economic situation might result in their being unable to meet travel and other costs associated with IPT. [18][19][20][21] Having no education or attaining only primary education was associated with a higher risk of LTFU. An earlier study by Wandwalo and Mørkve demonstrated significant differences in knowledge on TB disease and treatment according to the number of years of school education in Mwanza, Tanzania and its association with poor adherence and LTFU.…”

Tuberculosis in HIV-infected persons in British Columbia during the HAART era

“…Screening uptake and LTBI treatment completion both appear to be suboptimal in real world conditions, despite the high risk of TB in HIV-infected individuals. 9,10 Interferon gamma release assays (IGRAs) could potentially be used to improve screening uptake, as IGRAs can be drawn with other routine bloodwork after HIV diagnosis, and they do not require a 48-72 hour return visit for reading. 6 However, IGRAs present their own challenges, including a lack of long-term followup data in HIV-infected populations, and high rates of conversion and reversion on serial testing.…”