Adhesiveness of AcrySof to a collagen film

Nagata, Toyofumi; Minakata, Akira; Watanabe, Ikuo

doi:10.1016/s0886-3350(98)80325-8

Cited by 129 publications

(53 citation statements)

References 1 publication

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“…[18][19][20][21][22] Therefore, the removal of residual LECs reduces the chances of development of ACO and PCO. 23 Several mechanical and chemical means of intraoperative anterior capsule cleaning have also been proposed. Mechanical removal of the LECs is achieved using hydrodissection with rotation and cortical clean-up after phacoemulsification.…”

Section: Discussionmentioning

confidence: 99%

Impact of anterior capsule polishing on anterior capsule opacification after cataract surgery: a randomized clinical trial

Shah

Praveen

Kaul

et al. 2008

Eye

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Section: Discussionmentioning

confidence: 99%

Impact of anterior capsule polishing on anterior capsule opacification after cataract surgery: a randomized clinical trial

Shah

Praveen

Kaul

et al. 2008

Eye

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“…One factor that might influence LEC migration is adhesiveness between the IOL optic and the posterior capsule, which in turn might reflect adhesive properties of IOL materials [22,23], the design of the posterior convexity [7,19] and/or the mechanical force generated by compression of the haptics [27]. An acrylic IOL adheres to the lens capsule three times more strongly than the PMMA IOL, while a silicone IOL shows no adhesiveness in vivo or in vitro [22,23].…”

Section: Discussionmentioning

confidence: 99%

“…An acrylic IOL adheres to the lens capsule three times more strongly than the PMMA IOL, while a silicone IOL shows no adhesiveness in vivo or in vitro [22,23]. Strong adhesion of the acrylic IOL optic to the collagen membrane could have retarded LEC migration.…”

Section: Discussionmentioning

confidence: 99%

Inhibition of Lens Epithelial Cell Migration by an Acrylic Intraocular Lens in vitro

Kurosaka

Obasawa²,

Kurosaka³

et al. 2002

Ophthalmic Res

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We developed a new in vitro system to evaluate the effect of intraocular lenses (IOLs) on the migration of lens epithelial cells (LECs) and determined how acrylic and other IOLs influence LEC migration using this model. In an in vitro system, porcine LECs were cultured in a cell culture chamber insert, containing a collagen membrane, for 10 days with no IOL or with various types of IOLs. Migration of LECs beneath each IOL optic was observed with an inverted-phase microscope. The cell-free areas under the IOL optic, where the LECs had not migrated, were measured. Without IOL, LECs completely covered the collagen membrane within 5 days after plating (5.0 ± 0.0 days). Complete coverage was slowed by a silicone IOL (6.7 ± 1.2 days, p = 0.0305). LECs cultured with acrylic or with round- or sharp-edged polymethylmethacrylate (PMMA) IOLs did not completely cover the area. Ten days after initiating cultures, the cell-free areas under IOLs with sharp edges (acrylic, 41.1 ± 8.0%; sharp-edged PMMA, 60.9 ± 39.0%) were significantly larger than under IOLs with round edges (silicone, 0.0 ± 0.0%; round-edged PMMA, 1.5 ± 1.2%). A sharp edge may act as a barrier to LEC migration. Moreover, LEC migration under the acrylic IOL slowed after the LECs had crossed the barrier of the optic edge, perhaps due to acrylic adhesive properties. Only a few LECs reached the collagen membrane beneath the central 3 mm of the acrylic IOL. This new in vitro model was useful in evaluating the effect of various IOLs on LEC migration. Acrylic IOLs inhibited LEC migration by not only a sharp edge but also other factors, such as adhesive properties.

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“…In contrast, patients with preoperative spherical corneas are ideally suited for implantation of Acrysof lenses using the practically astigmatism-neutral 3.2-mm corneal tunnel. Besides the significant reduction of posterior capsular opacification [1, 2], a high postoperative stability [2, 13], low rates of infection [14, 15]and the possibility of sulcus fixation when a posterior capsular defect occurs [16], there are also refractive advantages to using the narrower 3.2-mm incision as demonstrated in this paper [3, 4, 13]. …”

Section: Discussionmentioning

confidence: 99%

Corneal Refractive Changes after Acrysof Lens versus PMMA Lens Implantation

Müller-Jensen

Barlinn²

2000

Ophthalmologica

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Purpose: Do foldable acrylic lenses yield not only reduced posterior capsular opacification but also significant refractive advantages? Patients and Methods: 147 cataract patients including 47 with spherical corneas and 100 with preoperative astigmatism of 0.8 ± 0.7 dpt were treated in one of two ways: 70 patients received 5.5-mm Acrysof lens implants through 3.2-mm outer and 4-mm inner temporal clear corneal openings (stretch incision); 77 patients received 5-mm PMMA lenses through temporal clear corneal incisions of 4.1-mm outer and 6.5-mm inner diameter incisions. Corneal topography was examined in all patients before the operations as well as 3 days and 6 months after the operations. Results: 6 months after the operations, we observed a surgically induced astigmatism of 0.4 ± 0.2 dpt for the 3.2-mm incisions compared to 0.8 ± 0.7 dpt for the 4.1-mm incisions; evaluation according to Holladay of the preoperative spherical corneas yielded a with-the-wound change of 0.0 ± 0.3 dpt after 3.2-mm incisions versus 0.6 ± 0.7 dpt after 4.1-mm incisions. The difference in astigmatism for the two types of incisions was statistically significant (p = 0.001). Conclusion: Acrysof lens implantation is especially useful for patients with spherical corneas because of avoidance of postoperative astigmatism. The 4.1-mm corneal incision using PMMA lens implants can be used on the steep meridian to reduce preoperative astigmatism.

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Adhesiveness of AcrySof to a collagen film

Abstract: AcrySof may have a strong tendency to adhere to the lens capsule, contributing to posterior and anterior capsule clarity and preventing lens decentration in vivo.

Cited by 129 publications

References 1 publication

Impact of anterior capsule polishing on anterior capsule opacification after cataract surgery: a randomized clinical trial

Impact of anterior capsule polishing on anterior capsule opacification after cataract surgery: a randomized clinical trial

Inhibition of Lens Epithelial Cell Migration by an Acrylic Intraocular Lens in vitro

Corneal Refractive Changes after Acrysof Lens versus PMMA Lens Implantation

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