Adiabatic Pulses for Wideband Inversion and Broadband Decoupling

Kupče, Ēriks; Freeman, Ray

doi:10.1006/jmra.1995.1179

Cited by 566 publications

(399 citation statements)

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“…Recently it has been shown that applying an adiabatic inversion to a single ST spinning sideband is enough to invert the entire ST manifold. Other adiabatic pulse shapes have also been proposed, including WURST [31] and DFS where the latter employs a constantamplitude pulse whose frequency is swept adiabatically [32]. Since QCPMG only involves manipulation of the spins during the acquisition, it is also possible to apply PT sequences prior to the QCPMG pulse train to provide further signal enhancement [33].…”

Section: Methods For Improving Sensitivity and Wideline Observation Fmentioning

confidence: 99%

Recent technique developments and applications of solid state NMR in characterising inorganic materials

Hanna

Smith

2010

Solid State Nuclear Magnetic Resonance

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A broad overview is given of some key recent developments in solid state NMR techniques that have driven enhanced applications to inorganic materials science. Reference is made to advances in hardware, pulse sequences and associated computational methods (e.g. first principles calculations, spectral simulation), along with their combination to provide more information about solid phases. The resulting methodology has allowed more nuclei to be observed and more structural information to be extracted. Cross referencing between experimental parameters and their calculation from the structure has seen an added dimension to NMR as a characterisation probe of materials. Emphasis is placed on the progress made in the last decade especially from those nuclei that were little studied previously. The general points about technique development and the increased range of nuclei observed are illustrated through a range of specific exemplars from inorganic materials science.

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Section: Methods For Improving Sensitivity and Wideline Observation Fmentioning

confidence: 99%

Recent technique developments and applications of solid state NMR in characterising inorganic materials

Hanna

Smith

2010

Solid State Nuclear Magnetic Resonance

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“…Shaped 13 C pulses (2 ms, Re-Burp profile [81], centered at 21.5 ppm, 800 MHz) are selective to excite primarily 13 C of Ala (along with other methyl spins). 13 Cα decoupling during t 1 is achieved using constant adiabaticity WURST-8 decoupling [82], sweeping from 50 to 58 ppm. A second field is applied, swept from -12 to -20 ppm, to reduce Bloch-Siegert effects for the Ala methyl 13 C spins [83].…”

Section: Noesy Distance Restraintsmentioning

confidence: 99%

“…13 C broad-band decoupling is achieved with a 2.6 kHz (max rf; 2.3 kHz rms) WURST-40 field centered at 75 ppm [82]. 15 N decoupling during acquisition was carried out using a WURST-2 field [82], with a bandwidth of 27 ppm, centered at 116. The Ala methyl region of the 1 H-13 C HSQC spectrum is characterized by a great deal of overlap.…”

Section: Noesy Distance Restraintsmentioning

confidence: 99%

Cross-Validation of the Structure of a Transiently Formed and Low Populated FF Domain Folding Intermediate Determined by Relaxation Dispersion NMR and CS-Rosetta

et al. 2011

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We have recently reported the atomic resolution structure of a low populated and transiently formed on-pathway folding intermediate of the FF domain from human HYPA/FBP11 [Korzhnev, D. M.; Religa, T. L.; Banachewicz, W.; Fersht, A. R.; Kay, L.E. Science 2011, 329, 1312–1316]. The structure was determined on the basis of backbone chemical shift and bond vector orientation restraints of the invisible intermediate state measured using relaxation dispersion nuclear magnetic resonance (NMR) spectroscopy that were subsequently input into the database structure determination program, CS-Rosetta. As a cross-validation of the structure so produced, we present here the solution structure of a mimic of the folding intermediate that is highly populated in solution, obtained from the wild-type domain by mutagenesis that destabilizes the native state. The relaxation dispersion/CS-Rosetta structures of the intermediate are within 2 Å of those of the mimic, with the nonnative interactions in the intermediate also observed in the mimic. This strongly confirms the structure of the FF domain folding intermediate, in particular, and validates the use of relaxation dispersion derived restraints in structural studies of invisible excited states, in general.

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“…In this communication, we report a new scheme for spectral editing based on the selective inversion obtained using the WURST pulse shape for adiabatic inversion [12,13]. WURST stands for Wideband, Uniform rate, Smooth Truncation: WURST operates at a lower peak radiofrequency field level than a hyperbolic secant pulse [10], prevents out-of-band excitation and inverts uniformly on a wide frequency range.…”

mentioning

confidence: 99%

“…3. The spectra were simulated with a spinning frequency of 10 kHz [12,13] adiabatic inversion pulse (τ = 5 ms, excitation width = 3 kHz, ν rf =5.5 kHz) with no enhancement. All experiments were performed on a Bruker DMX 400 spectrometer using a Bruker 2.5 mm MAS probehead.…”

mentioning

confidence: 99%

Spectral editing in solid-state MAS NMR of quadrupolar nuclei using selective satellite inversion

Dey

Prasad

Ash

et al. 2007

Journal of Magnetic Resonance

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Adiabatic Pulses for Wideband Inversion and Broadband Decoupling

Cited by 566 publications

References 0 publications

Recent technique developments and applications of solid state NMR in characterising inorganic materials

Recent technique developments and applications of solid state NMR in characterising inorganic materials

Cross-Validation of the Structure of a Transiently Formed and Low Populated FF Domain Folding Intermediate Determined by Relaxation Dispersion NMR and CS-Rosetta

Spectral editing in solid-state MAS NMR of quadrupolar nuclei using selective satellite inversion

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