Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of obesity to MASH

L’homme, Laurent; Sermikli, Benan Pelin; Haas, Joel T.; Fleury, Sébastien; Quemener, Sandrine; Guinot, Valentine; Barreby, Emelie; Esser, Nathalie; Caiazzo, Robert; Verkindt, Hélène; Legendre, Benjamin; Raverdy, Violeta; Cheval, Lydie; Paquot, Nicolas; Piette, Jacques; Legrand-Poels, Sylvie; Aouadi, Myriam; Pattou, François; Staels, Bart; Dombrowicz, David

doi:10.1038/s41467-024-51078-2

Nat Commun

2024

DOI: 10.1038/s41467-024-51078-2

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Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of obesity to MASH

Laurent L’homme,

Benan Pelin Sermikli,

Joel T. Haas

et al.

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Cited by 3 publications

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Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of obesity to MASH

Cited by 3 publications

References 64 publications

GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis

GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis

Starvation and infection: The role of sickness-associated anorexia in metabolic adaptation during acute infection

GDF-15 improves the predictive capacity of steatotic liver disease non-invasive tests for incident morbidity and mortality risk for cardio-renal-metabolic diseases and malignancies

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