2012
DOI: 10.1016/j.jnutbio.2011.05.008
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Adipose triglyceride lipase expression and fasting regulation are differently affected by cold exposure in adipose tissues of lean and obese Zucker rats

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Cited by 26 publications
(29 citation statements)
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“…It is well known that ␤-adrenergic stimulation, such as cold exposure, induces an increase of fatty acid catabolism, especially in WAT, while it decreases fatty acid synthesis (8,29). According to this, we observed increased expression of a key gene involved in fatty acid ␤-oxidation, Cpt1a, and decreased …”
Section: Discussionsupporting
confidence: 65%
See 1 more Smart Citation
“…It is well known that ␤-adrenergic stimulation, such as cold exposure, induces an increase of fatty acid catabolism, especially in WAT, while it decreases fatty acid synthesis (8,29). According to this, we observed increased expression of a key gene involved in fatty acid ␤-oxidation, Cpt1a, and decreased …”
Section: Discussionsupporting
confidence: 65%
“…Lrp10 was chosen as the housekeeping gene because it has been demonstrated to be a suitable reference gene for studies using adipose tissue and cold exposure (8,22). Primers for the different genes are described in Table 1 and were obtained from Sigma Genosys (Sigma-Aldrich Química).…”
Section: Methodsmentioning
confidence: 99%
“…The triacylglycerol (TG) content was measured in liver and muscle lipid extracts as previously described 18 using the Serum Triglyceride Determination Kit (Sigma Aldrich, Madrid, Spain).…”
Section: Triacylglycerol Determinationmentioning
confidence: 99%
“…ATGL expression increases during food deprivation in humans, rats, and seals [21, 23, 32] and so is likely responsible for the increased circulating FFA concentration during fasting. AMP-activated protein kinase (AMPk) activity has also been reported to increase with fasting in rats and elephant seals [19, 33, 34], and because its upregulation increases ATGL expression in vitro [35, 36], it is likely responsible for the increased ATGL expression in vivo during prolonged fasting.…”
Section: Mechanisms Regulating Substrate Availabilitymentioning
confidence: 99%