Adjunctive homeopathic treatment in patients with severe sepsis: a randomized, double-blind, placebo-controlled trial in an intensive care unit

Frass, Michael; Linkesch, Manfred; Banyai, S; Resch, G.; Dielacher, Christoph; Lobl, Thomas J; Endler, Christian; Haidvogl, M; Muchitsch, Ilse; Schuster, Ernst

doi:10.1016/j.homp.2005.01.002

Cited by 62 publications

(56 citation statements)

References 30 publications

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“…The question of whether homeopathy may treat critical illnesses such as sepsis and be useful in emergency conditions has been dealt with before now. [20][21][22] However, a word of caution must be added here. In India, all homeopathic physicians are medically trained doctors and therefore handling a septicemic case may be considered under their care.…”

Section: Discussionmentioning

confidence: 99%

Psoriasis cases of same diagnosis but different phenotypes—Management through individualized homeopathic therapy

Mahesh¹,

Shah

Mallappa³

et al. 2019

Clinical Case Reports

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Section: Discussionmentioning

confidence: 99%

Psoriasis cases of same diagnosis but different phenotypes—Management through individualized homeopathic therapy

Mahesh¹,

Shah

Mallappa³

et al. 2019

Clinical Case Reports

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“…A total of 22 trials (54%) reported both sample size calculations and intention to treat analyses. Eight trials (20%) did not report sample size calculations or intention to treat analyses (53,57,60,61,64,67,68,73). Four of these studies also had a methodological quality of B (medium quality) (53,64,67,73).…”

Section: Methodological Quality Of the Rctsmentioning

confidence: 99%

Adverse effects of homeopathy, what do we know? A systematic review and meta-analysis of randomized controlled trials

Kristoffersen

Alræk

Liu

2016

Complementary Therapies in Medicine

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Highlights:• This review address the naive assumption that because of the generally diluted doses used homeopathy must be safe• This review touches the neglected issue of the distinction between homeopathic aggravation, adverse reactions and adverse effects• We found a similar risk for homeopathic treatment compared to controls such as placebo and conventional medicine. Words: 5,187 Abstract ObjectivesHomeopathy is a popular treatment modality among patient, however there is sparse research about adverse effects of homeopathy. A concept unique for homeopathy, is homeopathic aggravation that is understood as a transient worsening of the patients' symptoms before an 2 expected improvement occurs. From a risk perspective it is vital that a distinction between homeopathic aggravations and adverse effects is established. There is a lack of systematic information on how frequent adverse effects and homeopathic aggravations are reported in studies. Therefore, a systematic review and meta-analysis were performed. Design and settingSixteen electronic databases were searched for Randomized Controlled Trials (RCTs). The searches were limited from the year 1995 to January 2011. Forty-one RCTs, with a total of 6.055 participants were included. A subtotal of 39 studies was included in the additional metaanalysis. ResultsA total of 28 trials (68%) reported adverse effects and five trials (12%) reported homeopathic aggravations. The meta-analysis (including six subgroup comparisons) demonstrated that no significant difference was found between homeopathy and control with OR 0.99, 95% CI 0.86 to 1.14, I 2 = 54%. More than two third of the adverse effects were classified as grade 1 (68%) and two third were classified as grade 2 (25%) and grade 3 (6%) according to the Common Terminology Criteria for Adverse Effects. Homeopathic aggravation was classified as grade 1 (98%) and grade 3 (2%), suggesting that homeopathic aggravations were reported to be less severe than adverse effects. The methodological quality according to a method recommended in the Cochrane handbook for RCTs, was high. ConclusionAdverse effects including the concept of homeopathic aggravations are commonly reported in trials. The meta-analysis demonstrated that the proportion of patients experiencing adverse effects to be similar for patients randomized to homeopathic treatment compared to patients randomized to placebo and conventional medicine.

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“…Auch am Inselspital Bern werden zusätzliche homöopathische Konsile in der Kinderonkologie angeboten, um die konventionelle Behandlung begleiten zu können [8]. Im AKH in Wien werden Tumorpatienten von Prof. Frass mit der Homöopathie begleitet und selbst auf der Intensivmedizin wird erfolgreich die Homöopathie eingesetzt [9]. Im Dr. Haunerschen Kinderspital der Phos.…”

Section: Diskussionunclassified

Zusatznutzen der Homöopathie in der Onkologie

Wurster¹

2018

DZO

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ZusammenfassungWeltweit werden onkologische Patienten mithilfe der Homöopathie begleitet, um die Nebenwirkungen der konventionellen Therapien wie Chemotherapien oder Bestrahlungen zu reduzieren. Es zeigt sich, dass Tumorpatienten, die zusätzlich homöopathisch behandelt werden, eine bessere Lebensqualität und ein längeres Gesamtüberleben aufweisen. Studien zur Tumorzellforschung zeigen die Wirkungen homöopathischer Hochpotenzen auf Tumorzelllinien. Tumorhemmende Effekte homöopathischer Mittel werden in vitro wie in vivo nachgewiesen. Komplementärmedizinische Forschungsprojekte (CAMbrella) und Forschungen zu personalisierten Immuntherapien und additiver Homöopathie öffnen den Weg für eine zukünftige integrative Onkologie.

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Adjunctive homeopathic treatment in patients with severe sepsis: a randomized, double-blind, placebo-controlled trial in an intensive care unit

Abstract: Our data suggest that homeopathic treatment may be a useful additional therapeutic measure with a long-term benefit for severely septic patients admitted to the intensive care unit. A constraint to wider application of this method is the limited number of trained homeopaths.

Cited by 62 publications

References 30 publications

Psoriasis cases of same diagnosis but different phenotypes—Management through individualized homeopathic therapy

Psoriasis cases of same diagnosis but different phenotypes—Management through individualized homeopathic therapy

Adverse effects of homeopathy, what do we know? A systematic review and meta-analysis of randomized controlled trials

Zusatznutzen der Homöopathie in der Onkologie

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