In two meta-analyses on gender differences in depression in nationally
representative samples we advance previous work by including studies of
depression diagnoses and symptoms to 1) estimate the magnitude of the gender
difference in depression across a wide array of nations and ages; 2) use a
developmental perspective to elucidate patterns of gender differences across the
lifespan; and 3) incorporate additional theory-driven moderators (e.g., gender
equity). For major depression diagnoses and depression symptoms, respectively,
we meta-analyzed data from 65 and 95 articles and their corresponding national
datasets, representing data from 1,716,195 and 1,922,064 people in over 90
different nations. Overall, OR = 1.95, 95% CI [1.88,
2.03] and d = 0.27 [0.26,
0.29]. Age was the strongest predictor of effect size. The gender
difference for diagnoses emerged earlier than previously thought, with OR
= 2.37 at age 12. For both meta-analyses, the gender difference peaked
in adolescence (OR = 3.02 for ages 13–15, and d
= 0.47 for age 16) but then declined and remained stable in adulthood.
Cross-national analyses indicated that larger gender differences were found in
nations with greater gender equity, for major depression, but not depression
symptoms. The gender difference in depression represents a health disparity,
especially in adolescence, yet the magnitude of the difference indicates that
depression in males should not be overlooked.