Adjusting for specificity of symptoms reveals higher prevalence of asymptomatic SARS-CoV-2 infections than previously estimated
Akshay Tiwari,
Shreya Chowdhury,
Ananthu James
et al.
Abstract:Accurate estimates of the prevalence of asymptomatic SARS-CoV-2 infections, ψ, have been important for understanding and forecasting the trajectory of the COVID-19 pandemic. Two-part population-based surveys, which test the infection status and also assess symptoms, have been used to estimate ψ. Here, we identified a widely prevalent confounding effect that compromises these estimates and devised a formalism to adjust for it. The symptoms associated with SARS-CoV-2 infection are not all specific to SARS-CoV-2.… Show more
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