2020
DOI: 10.4187/respcare.08557
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Administering Inhaled Nitric Oxide: Still More to Understand

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“…iNO has the potential to dilate blood vessels and has been shown to improve arterial oxygen partial pressure, improve ventilation/blood flow imbalance, reduce pulmonary hypertension and shunt in patients with acute respiratory failure. In about two-thirds of patients, iNO improves oxygenation and survival, but has no significant effect on reducing mechanical ventilation duration and mortality, and iNO can lead to renal insufficiency and other complications [20] . Alveolar surfactants have also been reported to be used in the treatment of aspiration injury, but there is still lacking of high-quality evidence that exogenous surfactants can be routinely used to treat…”
Section: Atomizing Inhalationmentioning
confidence: 99%
“…iNO has the potential to dilate blood vessels and has been shown to improve arterial oxygen partial pressure, improve ventilation/blood flow imbalance, reduce pulmonary hypertension and shunt in patients with acute respiratory failure. In about two-thirds of patients, iNO improves oxygenation and survival, but has no significant effect on reducing mechanical ventilation duration and mortality, and iNO can lead to renal insufficiency and other complications [20] . Alveolar surfactants have also been reported to be used in the treatment of aspiration injury, but there is still lacking of high-quality evidence that exogenous surfactants can be routinely used to treat…”
Section: Atomizing Inhalationmentioning
confidence: 99%