Administration of <i>Cyperus rotundus</i> tubers extract prevents weight gain in obese Zucker rats

Lemaure, Bernard; Touché, André; Zbinden, Irène; Moulin, Julie; Courtois, Didier; Macé, Katherine; Darimont, Christian

doi:10.1002/ptr.2147

Cited by 59 publications

(30 citation statements)

References 34 publications

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“…The binding assay performed on the rat beta3-AR isoform, known to induce thermogenesis, demonstrated that Cyperus rotundus tubers extract can consistently and effectively bind to this receptor. The data suggest that the effect on weight gain exerted by Cyperus rotundus tubers extract may be mediated, at least partially, through the activation of the beta3-AR [110].…”

Section: Hypolipidemic and Weight Control Effectmentioning

confidence: 92%

A review on Cyperus rotundus A potential medicinal plant

Al-Snafi¹

2016

IOSRPHR

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Abstract:-Many previous studies showed Cyperus rotundus contained flavonoids, tannins, glycosides, furochromones, monoterpenes, sesquiterpenes, sitosterol, alkaloids saponins, terpenoids, essential oils, starch, carbohydrates, protein, separated amino acids and many other secondary metabolites. The previous works also showed that the plant exerted antiparasitic, insecticidal, repellent, antibacterial, antioxidant, anticancer, central nervous, neuroprotective, antiinflammatory, antipyretic, analgesic, hypolipidemic, weight control, antiplatelet, gastrointestinal, hepatoprotective, antidiabetic, anti-dysmenorrhea, dermatological and many other effects. This review was designed to highlight the chemical constituents and pharmacological effects of Cyperus rotundus.

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Section: Hypolipidemic and Weight Control Effectmentioning

confidence: 92%

A review on Cyperus rotundus A potential medicinal plant

Al-Snafi¹

2016

IOSRPHR

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“…Therefore, there is a demand for therapeutically effective and safe anti-obesity agents. In previous studies, numerous oriental medicinal herbs were reported to be useful for controlling obesity and hyperlipidemia without significant side effects (7)(8).…”

Section: Introductionmentioning

confidence: 99%

Anti-obesity effects of Geranium thunbergii extract via improvement of lipid metabolism in high-fat diet-induced obese mice

Kim¹

2011

Mol Med Report

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Abstract. This study investigated the anti-obesity properties of an extract of Geranium thunbergii (GTE) in high-fat diet-induced obese mice. GTE treatment significantly reduced body weight, adipose tissue mass, adipocyte size, as well as serum triglyceride, total cholesterol and low-density lipoprotein-cholesterol levels in obese mice compared to high-fat diet-fed mice. It also decreased serum leptin levels and increased adiponectin levels. The serum levels of aspartate transaminase, alanine transaminase, blood urea nitrogen and creatinine were not significantly changed in GTE-treated mice compared to serum levels in normal diet and high-fat diet-fed mice. Furthermore, GTE suppressed the mRNA levels of sterol regulatory element-binding protein 1c, peroxisome proliferator-activated receptor γ, adipocyte fatty acid-binding protein and fatty acid synthase in the adipose tissues of obese mice. These results suggest that GTE ameliorated high-fat diet-induced obesity by altering the adipokine levels and downregulating the expression of transcription factors and lipogenic enzymes involved in lipid metabolism.

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“…An experimental study was performed on Rats show; Cyperus rotundus stopped weight gain and in vitro, stimulated lipolysis in 3T3F442 adipocytes 13 .…”

Section: Nidana Parivarjanamentioning

confidence: 99%

An Innovative Approach for Management of Obesity Through Ayurveda: A Review

Tiwari¹,

Srivastava²,

Manglesh³

2017

Int. J. Res. Ayurveda Pharm.

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Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on h ealth. Obesity is a leading but preventable cause of death worldwide. Incidences are increasing in adults and children due to fault y dietary habits including junk foods, lack of physical exercises and sedentary life style. Obesity increases the risk of many diseases such as cardiovascular diseases, type 2 diabetes, depression and hypertension etc. The main treatment for obesity consists of dieting and physical exercise. Dieting includes right choice of food substances which fulfil the energy requirements without increasing the body fat. In Ayurveda, this condition is named as Atisthula or Medo-roga. An extensive description pertaining to Medo-roga and its treatment is available in classical texts. In Ayurveda, treatment for obesity is based on guru (diet fulfilling energy requirements) and aptarpana (diet reducing body fat) chikitsa siddhanta (treatment modality).

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Administration of Cyperus rotundus tubers extract prevents weight gain in obese Zucker rats

Cited by 59 publications

References 34 publications

A review on Cyperus rotundus A potential medicinal plant

A review on Cyperus rotundus A potential medicinal plant

Anti-obesity effects of Geranium thunbergii extract via improvement of lipid metabolism in high-fat diet-induced obese mice

An Innovative Approach for Management of Obesity Through Ayurveda: A Review

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