ADNI Biomarker Core: A review of progress since 2004 and future challenges
Leslie M. Shaw,
Magdalena Korecka,
Edward B. Lee
et al.
Abstract:BACKGROUNDWe describe the Alzheimer's Disease Neuroimaging Initiative (ADNI) Biomarker Core major activities from October 2004 to March 2024, including biobanking ADNI cerebrospinal fluid (CSF), plasma, and serum biofluid samples, biofluid analyses for Alzheimer's disease (AD) biomarkers in the Biomarker Core and various non‐ADNI laboratories, and continuous assessments of pre‐analytics.RESULTSValidated immunoassay and mass spectrometry‐based assays were performed in CSF with a shift to plasma, a more accessib… Show more
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