Adolescents and young people at the centre: global perspectives and approaches to transform HIV testing, treatment and care

Archary, Moherndran; Pettifor, Audrey; Toska, Elona

doi:10.1002/jia2.25581

Cited by 13 publications

(13 citation statements)

References 20 publications

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“…Further longitudinal review of overall attendance and visit types at comparison clinics in the region is underway by this authorship team. Nonetheless, Girl Champ is consistent with other person-centered and gain-framed efforts to successfully engage AGYW in HIV services [55][56][57].…”

Section: Discussionsupporting

confidence: 71%

Girl Champ in eSwatini: A Strategic Marketing Campaign to Promote Demand for Sexual and Reproductive Health Services Among Young Women

Brault

Christie

Manchia³

et al. 2021

AIDS Behav

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Efforts to engage adolescent girls and young women (AGYW) in HIV services have struggled, in part, due to limited awareness of services and stigma. Strategic marketing is a promising approach, but the impact on youth behavior change is unclear. We report findings from a mixed methods evaluation of the Girl Champ campaign, designed to generate demand for sexual and reproductive services among AGYW, and piloted in three clinics in the Manzini region of eSwatini. We analyzed and integrated data from longitudinal, clinic-level databases on health service utilization among AGYW before and after the pilot, qualitative interviews with stakeholders responsible for the implementation of the pilot, and participant feedback surveys from attendees of Girl Champ events. Girl Champ was well received by most stakeholders based on event attendance and participant feedback, and associated with longitudinal improvements in demand for HIV services. Findings can inform future HIV demand creation interventions for youth.

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Section: Discussionsupporting

confidence: 71%

Girl Champ in eSwatini: A Strategic Marketing Campaign to Promote Demand for Sexual and Reproductive Health Services Among Young Women

Brault

Christie

Manchia³

et al. 2021

AIDS Behav

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“…In this review, we synthesized and meta-analysed randomized controlled trials assessing the effect of psychosocial interventions on engagement in care and health and behavioural outcomes for AYPLHIV. While a growing body of research has attempted to understand drivers of adolescent engagement in HIV care [99][100][101], as well as effective modes of improving health outcomes and reducing sexual risk behaviours in this age group [102,103], our systematic review and meta-analysis represents an important step toward establishing evidence for the effectiveness of psychosocial interventions to improve these outcomes for AYPLHIV.…”

Section: Discussionmentioning

confidence: 99%

Psychosocial interventions for improving engagement in care and health and behavioural outcomes for adolescents and young people living with HIV: a systematic review and meta‐analysis

et al. 2021

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Introduction: Adolescents and young people comprise a growing proportion of new HIV infections globally, yet current approaches do not effectively engage this group, and adolescent HIV-related outcomes are the poorest among all age groups. Providing psychosocial interventions incorporating psychological, social, and/or behavioural approaches offer a potential pathway to improve engagement in care and health and behavioural outcomes among adolescents and young people living with HIV (AYPLHIV). Methods: A systematic search of all peer-reviewed papers published between January 2000 and July 2020 was conducted through four electronic databases (Cochrane Library, PsycINFO, PubMed and Scopus). We included randomized controlled trials evaluating psychosocial interventions aimed at improving engagement in care and health and behavioural outcomes of AYPLHIV aged 10 to 24 years. Results and discussion: Thirty relevant studies were identified. Studies took place in the United States (n = 18, 60%), sub-Saharan Africa (Nigeria, South Africa, Uganda, Zambia, Zimbabwe) and Southeast Asia (Thailand). Outcomes of interest included adherence to antiretroviral therapy (ART), ART knowledge, viral load data, sexual risk behaviours, sexual risk knowledge, retention in care and linkage to care. Overall, psychosocial interventions for AYPLHIV showed important, small-tomoderate effects on adherence to ART (SMD = 0.3907, 95% CI: 0.1059 to 0.6754, 21 studies, n = 2647) and viral load (SMD = À0.2607, 95% CI À04518 to À0.0696, 12 studies, n = 1566). The psychosocial interventions reviewed did not demonstrate significant impacts on retention in care (n = 8), sexual risk behaviours and knowledge (n = 13), viral suppression (n = 4), undetectable viral load (n = 5) or linkage to care (n = 1) among AYPLHIV. No studies measured transition to adult services. Effective interventions employed various approaches, including digital and lay health worker delivery, which hold promise for scaling interventions in the context of COVID-19. Conclusions: This review highlights the potential of psychosocial interventions in improving health outcomes in AYPLHIV. However, more research needs to be conducted on interventions that can effectively reduce sexual risk behaviours of AYPL-HIV, as well as those that can strengthen engagement in care. Further investment is needed to ensure that these interventions are cost-effective, sustainable and resilient in the face of resource constraints and global challenges such as the COVID-19 pandemic.

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“…To start, the implementation science working sub-group invited nominations of possible implementation frameworks to inform harmonization efforts. Three were proposed to guide measurement selection in the consortium: a primarily determinants framework (Consolidated Framework for Implementation Research; CFIR Damschroder et al, 2009 ), a mostly evaluative framework (Reach Effectiveness Adoption Implementation Maintenance; RE-AIM Glasgow et al, 1999 ), and a largely process plus determinants framework (Exploration, Preparation, Implementation, Sustainment; EPIS Aarons et al, 2011 ). The working group drafted a summary document describing the objectives, constructs, and associated survey instruments for the three frameworks.…”

Section: Resultsmentioning

confidence: 99%

Harmonizing Implementation and Outcome Data Across HIV Prevention and Care Studies in Resource-Constrained Settings

Donenberg

Merrill

Obiezu-Umeh

et al. 2022

Glob Implement Res Appl

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Harmonizing measures across studies can facilitate comparisons and strengthen the science, but procedures for establishing common data elements are rarely documented. We detail a rigorous, 2-year process to harmonize measures across the Prevention And Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings (PATC 3 H) consortium, consisting of eight federally-funded studies. We created a repository of measured constructs from each study, classified and selected constructs for harmonization, and identified survey instruments. Measures were harmonized for implementation science, HIV prevention and care, demographics and sexual behavior, mental health and substance use, and economic assessment. Importantly, we present our harmonized implementation science constructs. A common set of implementation science constructs have yet to be recommended in the literature for low-to-middle-income countries despite increasing recognition of their importance to delivering and scaling up effective interventions. Drawing on RE-AIM (Reach Effectiveness Adoption Implementation Maintenance) and the Implementation Outcomes Framework, items were harmonized for staff/administrators and study participants to measure reach, adoption, implementation, maintenance, feasibility, acceptability, appropriateness, and fidelity. The process undertaken to harmonize measures and the codified set of implementation science measures developed by our consortium can inform future data harmonization efforts, critical to strengthening the replication and generalizability of findings while facilitating collaborative research—especially in resource-limited settings. We conclude with recommendations for research consortia, namely ensuring representation from all study teams and research priorities; adopting a flexible, transparent, and systematic approach; strengthening the literature on implementation science harmonization; and being responsive to life events (e.g., COVID-19). Supplementary Information The online version contains supplementary material available at 10.1007/s43477-022-00042-7.

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Adolescents and young people at the centre: global perspectives and approaches to transform HIV testing, treatment and care

Cited by 13 publications

References 20 publications

Girl Champ in eSwatini: A Strategic Marketing Campaign to Promote Demand for Sexual and Reproductive Health Services Among Young Women

Girl Champ in eSwatini: A Strategic Marketing Campaign to Promote Demand for Sexual and Reproductive Health Services Among Young Women

Psychosocial interventions for improving engagement in care and health and behavioural outcomes for adolescents and young people living with HIV: a systematic review and meta‐analysis

Harmonizing Implementation and Outcome Data Across HIV Prevention and Care Studies in Resource-Constrained Settings

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