Background: Mental health conditions represent 16% of the global burden of disease and injury in adolescents. Promotion, protection, and restoring the mental health must be considered indispensable, especially in adolescence. This study aims to verify the association of living practices, living with parents and the presence of Common Mental Disorders (CMD) in Adolescents.Methods: Cross-sectional study that analyzed data from 71,553 Brazilian adolescents aged 12-17 years, from the Study on Cardiovascular Risks in Adolescents (ERICA), between 2013-2014. Principal Component Analysis was performed to identify Living Practices Patterns, and Logistic Regression Models were performed to identify the associations between Living Practices Patterns, living with parents, and presence of CMD.Results: 71,553 adolescents were evaluated. To construct the Common Mental Disorders (CMD) variable, the Goldberg General Health Questionnaire was used. A pattern of Healthy Living Practices Standard (HLPS) was found. Adolescents belonging to the second (OR: 0.74; 95% CI 0.66–0.83) and third (OR: 0.45; 95% CI 0.39–0.51) terciles of the HLPS, that is, those who had higher rates of belonging to the pattern had lower chances of having CMD. Adolescents who lived with only the father or only the mother (OR: 1.25; 95% CI 1.09-1.43) or with no parent (OR: 1.59; 95% CI 1.27-1.99) were associated with a higher chance to present CMD.Conclusions: An inverse association between HLPS and the presence of CMD and a direct association between not living with both parents or living only with the mother or only with the father and the presence of CMD was identified.