Adrenal Disease and Pregnancy

Armas, Guadalupe Guijarro de

doi:10.5772/16944

Basic and Clinical Endocrinology Up-to-Date 2011

DOI: 10.5772/16944

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Adrenal Disease and Pregnancy

Guadalupe Guijarro de Armas¹

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2017

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References 35 publications

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Cushing’s Syndrome Complicating Pregnancy

Hung¹,

Ng²,

Wa³

2017

J Clin Case Rep

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To reveal Cushing's syndrome in pregnancy is difficult since there are no worldwide consent guidelines for making a definitive diagnosis. Some advocate using urine free cortisol as more than four times the upper limit of normal or salivary cortisol is two to three times above. It is also difficult to evaluate the optimal time of surgical intervention because most cases are diagnosed at or beyond their second trimester. In the case describe below, the disease was being suspected because there was a lost circadian variation of serum cortisol, which could be a reasonable initiate test for clinical suspicious cases in our further practice.Keywords: Cushing's syndrome; Pregnancy; Urine; Ultrasound Case ReportA 28-year-old pregnant woman who is free of past medical history was being referred to medical out-patient-department at gestational age 15 weeks with the complain of sensation of generalized distention over face, neck, hands and both lower limbs since Nov 2014. She enjoyed good past health and that was her first time of perception. The thyroid function test at that time revealed mildly lowered total T3, FT3 but normal FT4 and TSH levels and mildly increased morning cortisol level at 21.7 µg/dL (6.19 µg/dL to 19.43 µg/dL in nonpregnant women) during medical work up. To repeat her FT4 and TSH on 7 Aug 2015 revealed levels within normal range but the increased morning cortisol level remained at 20.04 µg/dL. The physical examination during her consultation showed no appreciable Cushingoid appearance i.e. moon faces, buffalo hump, truncal obesity, supraclavicular fat pads and her blood pressure was normal.

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Cushing’s Syndrome Complicating Pregnancy

Hung¹,

Ng²,

Wa³

2017

J Clin Case Rep

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Adrenal Disease and Pregnancy

Cited by 1 publication

References 35 publications

Cushing’s Syndrome Complicating Pregnancy

Cushing’s Syndrome Complicating Pregnancy

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