Adrenal Ewing's Sarcoma in an Elderly Man

Abstract

Ewing's sarcoma usually arises in the bones of children and adolescents. We herein report a 74-year-old man with Ewing's sarcoma in the adrenal gland. The diagnosis was confirmed by a genetic test, pathological studies, and several imaging studies. He already had multiple liver metastases when he was transferred to our hospital and died on the 37th day. The diagnosis was further confirmed by autopsy studies. Adrenal Ewing's sarcoma is very rare, and our patient was older than other reported cases. Ewing's sarcoma should be considered even in elderly patients with adrenal tumors.

Outcomes of Ewing sarcoma in adults over 40 years of age from a low-middle income country

“…One patient with poor performance status (PS), history of ischemic heart disease and disease progression in the 4 months gap between local therapy and the start of systemic therapy was offered first-line OMCT. Of patients who received any tumour-directed therapy [ 31 ], 20 (64.5%) completed the intended therapy.…”

“…Analysis of the SEER database from 1973–2008 revealed it to be 13.8% of all ES patients [ 30 ]. Approximately 10% were geriatric patients (over 60 years) in our study, and only a few case reports share their experience treating this rare population [ 31 – 35 ]. Extremities were the primary tumour location in 36.4% of cases, and this similar to other studies [ 16 , 36 ].…”

Abdominal distention, immunopositivity, and aggressive nature: A rare Ewing's sarcoma of the adrenal gland

“…ES typically affects young adults with a median age of 23.4 years at presentation [4] . A few reported patients were over 50 years old at diagnosis, with the oldest reported age of 74 [5] . A retrospective analysis of 18 cases of intra-abdominal and retroperitoneal neuroectodermal tumors reported a mean tumor diameter of 7.2 cm in contrast with our case, which measures twice as big, with a maximum diameter of 24 cm [6] .…”