Adrenal myelolipoma: a comprehensive review

Abstract

The average age for its diagnosis was 51 years, and no gender difference was observed. The average size of tumors was 10.2 cm. Congenital adrenal hyperplasia was associated to 10% of all cases analyzed, while other adrenal hypersecretory disorders (cortisol, aldosterone) were found in 7.5% of cases. Computed tomography and magnetic resonance imaging can be reliably used for its differential diagnosis. If the diagnosis of an adrenal myelolipoma is unambiguous, and no associated symptoms or hormonal activity are established, surgical intervention is usually not necessary.

Are there any Connections between Adrenal Myelolipoma and Hypertension?

“…Based on our study, AML patients were usually diagnosed at the age of 49.77±11.64 on average, which is in consistence with the report of Decmann A[5] who reviewed 440 cases of AML with mean age of 51 ±14.4. The incidence of AML with hypertension in our study is 31.7%, while 22.3% of AML with hypertension was reported by Decmann A [5]. It seems that there may exist some intrinsic connections between AML and hypertension.…”

“…However, some are diagnosed with AML due to lumbar pain, abdominal pain, dizziness, abnormal level of hormones and so on [4,5]. Some patients present with hypertension and are eventually diagnosed as AML by histopathological biopsy.…”

Feocromocitoma relacionado a mielolipoma

“…El mielolipoma es una tumoración benigna, usualmente no funcionante, compuesto por tejido adiposo maduro y células hematopoyéticas, y que se encuentra en la lista de los tumores estromales y mesenquimatosos de la corteza adrenal según la última actualización de tumores endocrinos de la WHO. 8 El mielolipoma rara vez pueden ser extraadrenal (mediastino, bazo, riñón, huesos, tórax, cavidad nasal, corteza suprarrenal ectópica, extradural o en los ojos).…”

“…En la tomografía, los valores de atenuación de -90 a -120 HU son característicos del tejido adiposo, y la presencia de densidad de grasa es útil y fundamental en el diagnóstico de una masa como un mielolipoma. 8 En el diagnóstico diferencial radiológico hay que considerar el liposarcoma retroperitoneal y el angiomiolipoma extrarrenal.…”

Bilateral Adrenal Myelolipomas Presenting as Acute Adrenal Insufficiency in an Adult With Congenital Adrenal Hyperplasia

“…However, a small number of AMs can be functional, resulting in hyperaldosteronism, hypercortisolism or hyperandrogenism 1 . It is recommended to use clinical judgment to determine the need of hormonal work-up.…”