Adrenal Scintiphotographic Study with 131I-Adosterol

Sasaki, Tsuneo; Ohno, Akiko; Tanaka, Yoshiaki; Ohshima, Motoo; Matsubara, Kazuhito; Makino, Nobuichi; Mishima, Atsushi; Yamaguchi, Hiroshi

doi:10.3769/radioisotopes.25.2_94

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1976

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“…In all three cases presented above, scintigraphy with Adosterol provided valuable diagnostic information and made it possible to make a therapeutic decision. Sasaki et al (9) also contend that the study is useful in detecting the presence and size of the lesion, although they found that some normal adrenal glands may not be visualized. In Case 1 the remnant of adrenal tissue was localized facilitating the surgery planned because of everincreasing clinical symptoms of hypercorticism.…”

Section: Discussionmentioning

confidence: 99%

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Adrenal Scintigraphy with 131I-Adosterol

Kasperlik-Załuska¹,

Chomicki²,

Hartwig³

et al. 1976

Nuklearmedizin

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SummaryA new adrenal scanning agent, Adosterol (131I-6β-iodomethyl-19-norcholest-5(10)-en-3β-ol) has been evaluated in three female patients with hypercortic-ism. In one case, characterised by recurrent adrenocortical hyperactivity after bilateral adrenalectomy, a remnant of adrenal tissue was detected. In two other cases, the presence of an adrenal tumour could be excluded. The scan made on the 6th day after the administration of Adosterol was found to be superior in quality to that made on the 13th day.

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Section: Discussionmentioning

confidence: 99%

“…Recently studies have been made (6,9) on the production and use of 131 I-6ß-Iodomethyl-19-norcholest-5(10)-en-3ß-ol (Adosterol) produced and distributed by Byk-Mallinckrodt.…”

Section: Introductionmentioning

confidence: 99%