Adrenergic drugs for urinary incontinence in adults

Alhasso, Ammar; Glazener, Cathryn; Pickard, Robert; N’Dow, James

doi:10.1002/14651858.cd001842

Cited by 29 publications

(18 citation statements)

References 20 publications

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“…63,64 These drugs are neither licensed for this treatment indication nor recommended by current guidance, 43 and were considered to be very rarely used in practice by our expert group. On this basis, the use of adrenergic agonists as a treatment option for SUI was not considered further.…”

Section: Adrenergic Agonistsmentioning

confidence: 99%

“…50,56,60,64,68,71,[83][84][85]87,88,106,201,[224][225][226][227][228] What our study has added is the systematic review and overview of the treatments relevant to the NHS, where evidence on the relative effectiveness has been derived using more advanced methods of meta-analysis than have been used previously. These methods have allowed us to provide clearer evidence about which treatments work and how well they work than was hitherto available.…”

Section: Strengths Assumptions Limitations and Uncertaintiesmentioning

confidence: 99%

See 1 more Smart Citation

Systematic review and economic modelling of the effectiveness and cost-effectiveness of non-surgical treatments for women with stress urinary incontinence

Imamura

Abrams²,

Bain³

et al. 2010

Health Technol Assess

Self Cite

168

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How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Contact details are as follows:Synergie UK (HTA Department) Digital House, The Loddon Centre Wade Road Basingstoke Hants RG24 8QW Email: orders@hta.ac.uk Tel: 0845 812 4000 -ask for 'HTA Payment Services' (out-of-hours answer-phone service) Fax: 0845 812 4001 -put 'HTA Order' on the fax header Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address. Paying by credit cardYou can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume. How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment programmeT he Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service'. The HTA programme is needs led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projec...

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Section: Adrenergic Agonistsmentioning

confidence: 99%

Section: Strengths Assumptions Limitations and Uncertaintiesmentioning

confidence: 99%

Systematic review and economic modelling of the effectiveness and cost-effectiveness of non-surgical treatments for women with stress urinary incontinence

Imamura

Abrams²,

Bain³

et al. 2010

Health Technol Assess

Self Cite

168

View full text Add to dashboard Cite

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“…Vingt-deux études randomisées sont retenues dont 11 en crossover et huit autres randomisées contre placebo, double insu de groupes parallèles. L'inclusion totalise 1 099 femmes dont 713 recevant une molécule d'action adrénergique (phenylpropalamine dans 11 études, midodrine dans deux, norépinéphrine dans trois, clenbutérol dans trois, terbutaline dans une, eskornade dans une et Ro 115-1240 dans une) avec comparaison à la rééducation périnéale dans deux études [53][54][55][56][57][58][59][60][61][62][63][64][65][66][67]. Toutes les femmes incluses pré-sentent une incontinence urinaire à l'effort, identifiée sur un bilan urodynamique sauf dans deux études : inclusion sur questionnaire de symptômes [62] et inclusion de patientes présentant une incontinence mixte [67].…”

Section: Molécules Adrénergiquesunclassified

Le traitement conservateur de l’incontinence urinaire d’effort de la femme

Denys

Kerdraon

2010

Pelv Perineol

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But : Regrouper des niveaux de preuve et/ou des grades de recommandation issus d'une revue de la littérature relative aux traitements non chirurgicaux de l'incontinence urinaire chez la femme. Matériel et méthodes : Revue systématique par recherche numérique dans Medline, Cinahh, Cochrane Library, National Library for Health (NLH), en appliquant lorsque possible des niveaux de preuve et/ou de grades de recommandations selon les critères énoncés par la HAS. Résultats : Soixante-douze études contrôlées randomisées et huit revues de la Cochrane Library ont été identifiées dans le champ des traitements conservateurs de l'incontinence urinaire chez la femme. Conclusion : Il existe des niveaux de preuve pour établir que le renforcement musculaire du plancher périnéal et les programmes de rééducation comportementale peuvent guérir l'incontinence urinaire chez la femme. En cas de surpoids, la perte de poids améliore l'incontinence urinaire. La duloxétine améliore l'incontinence et la qualité de vie, mais sa place n'est actuellement pas déterminée dans l'algorithme des traitements conservateurs. Les effets de l'électrostimula-tion périnéale et de l'estrogénothérapie sont inconstants ou inhomogènes.Mots clés Incontinence urinaire · Femme · Traitement conservateur · Niveau de preuve Abstract Objectives: To synthetize evidence-based results related to nonsurgical management for urinary incontinence in women. Materials and methods: Electronic search in Pubmed, Cinahl, Cochrane Library, and National Library for Health. Results: There were 72 randomized control studies and eight review from the Cochrane Library. Conclusion: Moderate to high levels of evidence suggest that weight loss from obesity state, pelvic muscle training, and bladder training may resolve urinary incontinence in women. The effects of electrical stimulation of pelvic floor, oestrogene therapy were inconstant or inhomogeneous. Duloxetine may improve continence and quality of life, but its range in therapeutic algorithm is still to be defined.

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“…Alpha-adrenergics such as phenylpropanolamine have been tried but have resulted in bothersome side effects and inconsistent outcomes. The recommendation of the Cochrane review was that these drugs were not helpful for SUI [22].…”

Section: Drug Therapymentioning

confidence: 99%

What’s a ‘cure’? Patient-centred outcomes of treatments for stress urinary incontinence

Freeman

2006

Int Urogynecol J

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Adrenergic drugs for urinary incontinence in adults

Cited by 29 publications

References 20 publications

Systematic review and economic modelling of the effectiveness and cost-effectiveness of non-surgical treatments for women with stress urinary incontinence

Systematic review and economic modelling of the effectiveness and cost-effectiveness of non-surgical treatments for women with stress urinary incontinence

Le traitement conservateur de l’incontinence urinaire d’effort de la femme

What’s a ‘cure’? Patient-centred outcomes of treatments for stress urinary incontinence

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