Adrenergic mechanism inTetrahymena. I. Changes in monoamine oxidase activity during growth

Phylogeny and Ontogeny of Hormone Receptors: The Selection Theory of Receptor Formation and Hormonal Imprinting

“…of Tetrahymena, to some hormones of higher animals can nevertheless result in interaction, followed by a demonstrable response. This takes place when Tetrahymena is treated with epinephrine (Iwata & Kariya, 1973; Kariya, Saito & Iwata, 1974; Kassis & Kindler, 1975; Rosenzweig & Kindler 1972) or serotonin (Rosenzweig & Kindler, 1972), and also during the action of the juvenile hormone on Chritidia (Injeyan & Meerowitch, 1974).…”

Biogenic amines at a low level of evolution: Production, functions and regulation in the unicellular Tetrahymena

“…The highest affi nity of the enzyme was for tryptamine and the less to dopamine. The activity was higher in the stationary phase than in the logarithmic one [36]. MAO blocker deprenyl increased serotonin content, but serotonin reuptake inhibitor fl uoxetine and MAO-A blocker clorgyline were ineffective [37].…”

Change in Catecholamine Content of Tetrahymena Pyriformis W During Growth

“…In our laboratory it was discovered that this protozoan contained the system catalysing the oxidation of biogenic monoamities and diamine (2). It was also found that in cultures of 7etraln'inena monoamine oxidise activity decreased in the exponential growth phase (EGP) and increased in the stationary tyrowth phase (SCP) (3) . The present work was on the change of the endogenous CA level and the rate of conversion of tyrosine to CA during growth of this protozoan.…”

“…Tcirahywiena pnriforinis W was cultured as reported previously (3). After culture for various periods, cells were treated with 0.4 N perchloric acid following the procedure of .Janakidevi ci al.…”