Adsorption of Albumin on Silica Surfaces Modified by Silver and Copper Nanoparticles

Abstract

Silver and copper nanoparticles, respectively, were produced on glass slides via magnetron sputtering. The experiments show that with magnetron sputtering the size and concentration of the nanoparticles can be easily controlled via sputter time and plasma power. Silver nanoparticles grow much faster than copper nanoparticles, which also require higher plasma power for their synthesis. Exposed to albumin solution, the glass slides with silver nanoparticles clearly show a delay in albumin attachment compared to pure glass slides. Glass slides with copper nanoparticles show a slight attachment of albumin even after 3 h of exposure. However, the albumin concentration on the surface of the glass slides was much smaller compared to pure glass slides and did not increase within 24 h.

Biotribological behavior of Ag–ZrCxN1−x coatings against UHMWPE for joint prostheses devices

“…6. Recent investigations have found that silver nanoparticles on surfaces may delay the adsorption of the albumin (Kumari et al, 2013), and therefore, the system may be less protected by the albumin as the silver nanoparticles increase in the material. The hydrophobic character of the samples also influences the albumin adsorption, as explained in the previous section, thus, the high wear rate exhibited by the sample ZrCN1 may also be due to low albumin adsorption as it is indeed the single sample showing a hydrophilic character.…”

Synthesis of Copper Nanoparticles Using Mixture of Allylamine and Polyallylamine

“…In particular, copper nanoparticles (Cu-NPs) are of great interest because of their distinctive catalytic, optical, thermal, magnetic, antimicrobial, electronic, and electrical conducting properties [3][4][5][6][7][8][9]. They present a wide range of potential applications in nanotechnology including catalysts [3], additives for lubricants [10], heat transfer nanofluids [11], manufacture of electronic and optical devices [12], conductive inks [13], materials for solar energy conversion [14], biosensors [15], antibiofouling agents [16], and cancer cell treatments [17]. Moreover, copper nanoparticles can be a promising candidate to replace expensive noble metal nanoparticles such as silver and gold [18][19][20].…”

Modulatory Effect of Citrate Reduced Gold and Biosynthesized Silver Nanoparticles on α-Amylase Activity

“…Gold nanoparticles present an alternate and advantageous synthetic scaffold for targeting protein surfaces [28] and have been demonstrated to bind biomacromolecules, [29] facilitate DNA transfection [30], and reversibly inhibit enzymes [31]. The binding of albumin protein on the surfaces of silver and gold nanoparticles has been studied for surface adhesion by researchers to understand the effect on its structural changes [32,33]. Biointeraction studies with AgNPs and protein and its SPR effect, surface charge effect was studied for various applications in biological sciences by various researchers [34,35].…”