Adsorption of Carboxymethylcyclodextrins on Cationic Liposomes as a Route for Preparation of Capacious Nanocontainers for the Hydrophobic Molecules
Vladislava Pigareva,
Elena Gorbunova,
Tatiana Dubinina
et al.
Abstract:Electrostatic self‐assembly of anionic carboxymethyl cyclodextrins (CMCDs) on the surface of cationic liposomes is investigated. By means of laser microelectrophoresis, dynamic light‐scattering, and atomic force microscopy the structure and composition of interfacial complexes at lipid membrane‐water interphase are analyzed. Incorporation of hydrophobic molecules in CMCDs is studied by UV‐Vis spectroscopy. Liposomes decorated with CMCDs are shown to pose low cytotoxicity up to relatively high concentration – 1… Show more
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