Adsorption of Free Hemoglobin by Electrochemically Modified Activated Carbons. Part 2. Blood Plasma

Khubutiya, M. Sh.; Tsivadze, А. Yu.; Garaeva, G.; Андреев, В. Н.; Goldin, Mark M.

doi:10.6060/mhc2012.120987g

Cited by 3 publications

(2 citation statements)

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“…In the initial Er, the cell count was 8,64 × 10 12 /L, while the relative amounts of the various erythrocyte morphologies (normal discocytes, echinocytes, ghosts) were, respectively, 80%, 17% and 3%. In the Er/hEr 1:1 mixture they were 21% (1,81×10 12 /L), 27% (2,33 × 10 12 /L) and 52% (4,5 × 10 12 /L), respectively.…”

Section: Methodsmentioning

confidence: 96%

“…Despite the obvious interest in, and practical importance of, the removal of erythrocyte ghosts from hemolyzed blood, free hemoglobin removal has received much greater attention in literature. 12 One exception is our recent work, 13 where the possibility of adsorption separation of normal and "ghost" red blood cells (RBC) using electrochemically controlled sorption on modified activated carbons was shown for the first time.…”

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confidence: 99%

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The Electrochemical Nature of Erythrocyte Interaction with Activated Carbons

Khubutiya

Goroncharovskaya

Goldin

et al. 2016

J. Electrochem. Soc.

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The effect of activated carbon potential on the interaction of carbon with erythrocytes was investigated. A significant contribution of carbon potential in the mechanism of adsorption was elucidated via the counterintuitive observation that the maximum of erythrocyte adsorption occurred on the carbon brand with the lowest specific macropore volume, as compared with several carbons of various origins with much larger specific macropore volumes. It was observed that maximum adsorption activity of the FAS activated carbon toward erythrocyte ghosts occurs at potentials near −100 mV. Microphotographs of electrochemically modified activated carbon samples after contact with hemolyzed erythrocytes carbons showed the carbon surface covered with stained ghost cells, corroborating the electrosorption character of the interaction. This adsorption occurred exclusively in carbon macropores. It was shown that a mixture of normal-morphology erythrocytes and erythrocyte ghosts can be separated by electrosorption on electrochemically modified activated carbons.

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Section: Methodsmentioning

confidence: 96%

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confidence: 99%