Adsorption of<i>β</i>-glucuronidase and estrogens on pectin/lignin hydrogel particles

Borisenkov, Mikhail F.; Карманов, А. П.; Кочева, Л. С.; Markov, Pavel A.; Истомина, Е. И.; Bakutova, Larisa A.; Litvinets, Sergey G.; Martinson, Ekaterina A.; Durnev, Eugene A.; Vityazev, Fedor V.; Popov, Sergey

doi:10.1080/00914037.2015.1129955

Cited by 19 publications

(8 citation statements)

References 40 publications

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“…It was found that the surface morphology depends on the sugar composition and macromolecular structure, as well as the polymer composition of the pectin gel . The surface morphology of gels formed from pectin isolated from callus culture cells was dependent on the conditions of the culture medium .…”

Section: Resultsmentioning

confidence: 99%

Mechanical properties, structure, bioadhesion, and biocompatibility of pectin hydrogels

Markov

Krachkovsky

Durnev

et al. 2017

J Biomedical Materials Res

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The surface structure, biocompatibility, textural, and adhesive properties of calcium hydrogels derived from 1, 2, and 4% solutions of apple pectin were examined in this study. An increase in the pectin concentration in hydrogels was shown to improve their stability toward elastic and plastic deformation. The elasticity of pectin hydrogels, measured as Young's modulus, ranged from 6 to 100 kPa. The mechanical properties of the pectin hydrogels were shown to correspond to those of soft tissues. The characterization of surface roughness in terms of the roughness profile (Ra) and the root-mean-square deviation of the roughness profile (Rq) indicated an increased roughness profile for hydrogels depending on their pectin concentration. The adhesion of AU2% and AU4% hydrogels to the serosa abdominal wall, liver, and colon was higher than that of the AU1% hydrogel. The adhesion of macrophages and the non-specific adsorption of blood plasma proteins were found to increase as the pectin concentration in the hydrogels increased. The rate of degradation of all hydrogels was higher in phosphate buffered saline (PBS) than that in DMEM and a fibroblast cell monolayer. The pectin hydrogel was also found to have a low cytotoxicity. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 2572-2581, 2017.

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Section: Resultsmentioning

confidence: 99%

Mechanical properties, structure, bioadhesion, and biocompatibility of pectin hydrogels

Markov

Krachkovsky

Durnev

et al. 2017

J Biomedical Materials Res

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“…In turn, starch-based films made by casting technique have already been studied, such as starch/pectin [1,[11][12][13][14] and starch/lignin-based films [10,15]. However, there are few studies on films obtained by extrusion, including starch/ pectin [16,17] and starch/lignin-based films [18], while pectin/lignin blends have been investigated only for the production of hydrogels as biomedical materials [19]. Thus, the objective of this study was to evaluate the properties of thermoplastic starch/pectin films, with the incorporation of lignin microparticles, since the mixture of these materials was not found in the research already carried out.…”

Section: Introductionmentioning

confidence: 99%

Effect of the incorporation of lignin microparticles on the properties of the thermoplastic starch/pectin blend obtained by extrusion

Begali

Ferreira

Oliveira

et al. 2021

International Journal of Biological Macromolecules

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“…A hydrophilic supramolecular complex of hemicellulose/oak lignin hydrogel with pectin embedded in the 3D structure was prepared and tested to deliver β-glucuronidase and estrogens [446].…”

Section: Bioactive Compounds Deliverymentioning

confidence: 99%

New Developments in Medical Applications of Hybrid Hydrogels Containing Natural Polymers

Vasile¹,

Pamfil²,

Stoleru³

et al. 2020

Molecules

211

131

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New trends in biomedical applications of the hybrid polymeric hydrogels, obtained by combining natural polymers with synthetic ones, have been reviewed. Homopolysaccharides, heteropolysaccharides, as well as polypeptides, proteins and nucleic acids, are presented from the point of view of their ability to form hydrogels with synthetic polymers, the preparation procedures for polymeric organic hybrid hydrogels, general physico-chemical properties and main biomedical applications (i.e., tissue engineering, wound dressing, drug delivery, etc.).

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Adsorption ofβ-glucuronidase and estrogens on pectin/lignin hydrogel particles

Cited by 19 publications

References 40 publications

Mechanical properties, structure, bioadhesion, and biocompatibility of pectin hydrogels

Mechanical properties, structure, bioadhesion, and biocompatibility of pectin hydrogels

Effect of the incorporation of lignin microparticles on the properties of the thermoplastic starch/pectin blend obtained by extrusion

New Developments in Medical Applications of Hybrid Hydrogels Containing Natural Polymers

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