Adsorption semiconductor sensor for diabetic ketoacidosis diagnosis

Makisimovich, N.; Vorotyntsev, V. B.; Nikitina, N. I.; Kaskevich, O.; Karabun, P.; Martynenko, F.

doi:10.1016/s0925-4005(97)80107-4

Cited by 87 publications

(37 citation statements)

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“…Acetone is a commonly used chemical reagent in industry, For instance it is used to dissolve plastics, purify paraffin, dehydrate tissues and for pharmaceutical applications. Several techniques have been developed to measure the concentration of acetone, such as gas/liquid chromatographic analysis, spectroscopy and sensors [8][9][10] . PMMA/CNT polymer composites 11,12 and conductive polymer composites 13 have been developed as sensors.The present work reports the results of the gas sensing behavior of a sensor developed using thick film which shows a maximum response to the test gas at room temperature.…”

Section: Introductionmentioning

confidence: 99%

Sensing of Acetone Vapours using Polymer Composite

Devikala¹,

Kamaraj²,

Arthanareeswari³

2016

Orient. J. Chem

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People may develop a headache, fatigue and even narcosis when the concentration of acetone in air is higher than 10,000 ppm. Hence, detecting and measuring acetone concentrations in the workplace or human body are necessary for our safety and health. Gas sensors play vital role in detecting, monitoring and controlling the presence of hazardous and poisonous gases in the atmosphere at very low concentrations. In the present work, a thick film of composite was prepared by using PMMA and TiO 2 (PMTi). Then, the composite's gas sensing behaviour for acetone vapour was tested by measuring the resistance change of the composite at room temperature. An increase in resistance has been observed with a response time of about ten seconds. The PMMA/ TiO 2 (PMTi) composites were characterized by using PXRD, FTIR and SEM. The results show that the thick film of PMTi composite can function as a very good gas sensor for acetone vapours.

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Section: Introductionmentioning

confidence: 99%

Sensing of Acetone Vapours using Polymer Composite

Devikala¹,

Kamaraj²,

Arthanareeswari³

2016

Orient. J. Chem

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“…Science has shown that the acetone concentration of exhaled breath is proportional to the content of acetone in the bloodstream which, in high levels, is linked to the presence of ketoacidosis, a side effect of uncontrolled diabetes [14]. Therefore, the amount of acetone in the breath is a biomarker for diabetes, meaning that a breath detector to diagnose diabetes is very much a possibility [14]. CHWs would be able to utilize this breathalyzer to market a preliminary screening test for diabetes.…”

Section: Diabetesmentioning

confidence: 99%

Breath and Air Analysis: Applications in Resource-poor Settings

Riley

Krisher

Mehta

2015

Procedia Engineering

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Recent research developments have led to the emergence of various portable and affordable gaseous-compound detecting devices. These non-invasive technologies detect volatile organic compounds in human breath or air, providing important information about us and our environment. While many of these technologies have been seamlessly integrated into Western countries, they have yet to be leveraged in developing nations. These devices can be used to easily and affordably screen patients for diabetes, monitor air quality of cities, and facilitate agricultural intensification. This article describes five scenarios where breath and air analysis technologies can address problems faced by populations in resource-poor settings.

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“…As a few applicative examples, a semiconducting-oxidebased chemiresistive microsensor [104] and a sensor system based on the Kelvin probe techniques with a Cu-phthalocyanine dye as the gas sensitive layer [105] for the measurement of NO/NO 2 in human breath, and a multisensory microsystem for the simultaneous measurement of peak expiratory flow, temperature, relative humidity, and pressure [106], have been proposed for the diagnosis of pulmonary disease and asthma. An eight-quartz microbalance-based sensor [105], a semiconducting oxidebased sensor [107] and a light addressable potentiometric sensor [108] were used to estimate the acetone concentration, a marker for diabetes, in breath samples. A quartz crystal microbalance modified with specific oligopeptides [109] was used to distinguish the breath of healthy volunteers from the breath of uremic patients, both before and after dialysis.…”

Section: Sensor-based Systemsmentioning

confidence: 99%

“…These experiments highlighted a decrease in acetone concentration in breath corresponding to the increase of glucose level in blood, but it was not possible to discriminate healthy subjects from subjects diagnosed as early diabetics. A considerable literature is available concerning sensor methods developed to monitor breath gases in diabetic patients, pointing out the great interest about this research theme [170][171][172]. Large interest has also been devoted to lung diseases, inflammatory states, and oncological processes, as well as to transplanted patients and organ failures such as liver and kidney.…”

Section: Breath Markers and Pathological Conditionsmentioning

confidence: 99%