Adsorption Studies on Clays III**Department of Pharmacy, Philadelphia College of Pharmacy and Science, Philadelphia, Pa.

Barr, Martin; Arnista, Edward S.

doi:10.1002/jps.3030460811

Cited by 8 publications

(2 citation statements)

References 12 publications

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“…54 Comparing the adsorption of diphtheria toxin by several clays, HNTs displayed superior adsorption properties than kaolin. 119 HNTs showed a strong adsorption capacity for pathogenic S. aureus and a slightly weaker capacity for E. coli. 120 Quaternized HNTs possessed higher porosity, surface area, and abundant surface amide groups, which made them suitable for the enrichment of bioactive molecules such as heparin from pig intestinal mucosa.…”

Section: Gastrointestinal Disease Treatmentmentioning

confidence: 94%

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The Horizons of Medical Mineralogy: Structure-Bioactivity Relationship and Biomedical Applications of Halloysite Nanoclay

Feng,

Chen,

et al. 2024

ACS Nano

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Medical mineralogy explores the interactions between natural minerals and living organisms such as cells, tissues, and organs and develops therapeutic and diagnostic applications in drug delivery, medical devices, and healthcare materials. Many minerals (especially clays) have been recognized for pharmacological activities and therapeutic potential. Halloysite clay (Chinese medicine name: Chishizhi), manifested as onedimensional aluminum silicate nanotubes (halloysite nanotubes, HNTs), has gained applications in hemostasis, wound repair, gastrointestinal diseases, tissue engineering, detection and sensing, cosmetics, and daily chemicals formulations. Various biomedical applications of HNTs are derived from hollow tubular structures, high mechanical strength, good biocompatibility, bioactivity, and unique surface characteristics. This natural nanomaterial is safe, abundantly available, and may be processed with environmentally safe green chemistry methods. This review describes the structure and physicochemical properties of HNTs relative to bioactivity. We discuss surface area, porosity and surface defects, hydrophilicity, heterogeneity and charge of external and internal surfaces, as well as biosafety. The paper provides comprehensive guidance for the development of this tubule nanoclay and its advanced biomedical applications for clinical diagnosis and therapy.

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Section: Gastrointestinal Disease Treatmentmentioning

confidence: 94%

“…Comparing the adsorption of diphtheria toxin by several clays, HNTs displayed superior adsorption properties than kaolin . HNTs showed a strong adsorption capacity for pathogenic S. aureus and a slightly weaker capacity for E. coli .…”

Section: Biomedical Applicationsmentioning

confidence: 97%