To deal with emergencies like water shortages and water pollution, scientists have worked on making materials and technologies that function well enough. The current technologies are not ‘100%’ efficient at providing potable water. Therefore, it is essential to come up with new and better ways to purify water. Nanotechnology offers inventive water treatment techniques. Nanomaterials are fabricated with useful properties for adsorption, catalysis, sensing, and optoelectronics applications, such as reactivity, high-aspect ratio, controlled pore volume as well as electrostatic, hydrophilic, and hydrophobic interactions. Anions, metal ions, microorganisms, and organic compounds can be eliminated using nanoparticles (NPs). Minimal NP concentrations are required for water treatment, making their application cost-effective. Biopolymeric materials have a number of advantages over their synthetic counterparts due to their easy biodegradability and low impact on the environment. Because of their minimum toxicity, improved adsorption capability, excellent biodegradability, significant photocatalytic potential and biocompatibility, nanobiohybrids have a significant role in the field of water and wastewater treatment. This chapter summarizes various production methods of diversified nanobiohybrids synthesized in recent years, with a particular focus on nanobiocomposites.