Adult adrenal ganglioneuroblastoma: A rare case report

Abstract

Ganglioneuroblastoma is an uncommon malignant tumour, and it is extremely rare in adults. A 27-year-old woman was admitted to hospital complaining of commitment left loin pain for 7 months accompanied with fever for 1 day. Computed tomography (CT) scan shows a huge cystic solid mass among the rear of the pancreatic body and tail, inside of the spleen, and the top of the left kidney. Hormone examinations showed that the serum levels of glucocorticoid, aldosterone, norepinephrine, and epinephrine were normal. However, neuron-specific enolase (NSE) was significantly higher (289.46 ng/mL, normal level <16.3 ng/mL). Adrenal mass resection was scheduled. However, intraoperative separation was very difficult and adrenal tumour resection, resection of the pancreatic body and tail, left nephrectomy, and splenectomy were carried out. Pathological diagnosis was ganglioneuroblastoma.

Adrenal ganglioneuroblastoma with metastasis near the renal hilum in an adult female: A case report and review of the literature

“…When diagnosing GNB, its clinical presentations are generally non-specific. Among the 104 reported cases, symptoms predominantly arose from compression by the primary or metastatic lesions ( 8 , 35 , 47 , 60 , 62 , 65 ). Some GNB cases with endocrine activity presented with endocrine-related symptoms such as diarrhea and malaise ( 4 , 15 , 36 , 49 , 77 ).…”