Adult Chronic Bronchitis--Continuous Antibiotic Therapy

Macrolide antibiotics and the airway: antibiotic or non-antibiotic effects?

“…In chronic obstructive pulmonary disease (COPD), the concept of long-term, prophylactic antibiotic therapy has been proposed for many years [49][50][51][52][53]. In a more modern setting, it has been shown that clarithromycin attenuates emphysema development in smoke-exposed mice and also downregulates TNF-a-induced MMP-9 release from macrophages [54].…”

A clinical and pathological study of resistance to infection in chronic lymphatic leukemia

“…The patient received an indeterminate amount of cortisone for about 6 weeks with no notable effect. This patient was clinically and hematologically stable without treatment until May, 1954.…”

“…He was kept on intermittent TEM therapy until June, 1955, when the hemoglobin started to fall. The patient received an indeterminate amount of cortisone for about 6 weeks with no notable effect. There was progression of disease over the next few months.…”