Adult Congenital Heart Disease Survivors at Age 50 Years: Medical and Psychosocial Status

Rehan, Rajan; Kotchetkova, Irina; Cordina, Rachael; Celermajer, David S.

doi:10.1016/j.hlc.2020.05.114

Cited by 14 publications

(18 citation statements)

References 18 publications

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“…102 Of 121 patients with adult congenital heart disease in Australia with moderate or complex CCD, just more than 60% of those with TOF or CoA remained employed, and approximately half had been diagnosed with anxiety or depression. 103 In patients with HLHS, an older age at Fontan procedure and a history of sepsis were independent predictors of poor neurocognitive outcomes. 104 …”

Section: Congenital Cardiovascular Defects and Kawasaki Diseasementioning

confidence: 93%

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Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Tsao¹,

Aday²,

Almarzooq³

et al. 2022

Circulation

3,787

2,336

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Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update. The 2022 Statistical Update is the product of a full year’s worth of effort by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. This year’s edition includes data on the monitoring and benefits of cardiovascular health in the population and an enhanced focus on social determinants of health, adverse pregnancy outcomes, vascular contributions to brain health, and the global burden of cardiovascular disease and healthy life expectancy. Results: Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.

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Section: Congenital Cardiovascular Defects and Kawasaki Diseasementioning

confidence: 93%

Section: Congenital Cardiovascular Defects and Kawasaki Diseasementioning

confidence: 99%

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Tsao¹,

Aday²,

Almarzooq³

et al. 2022

Circulation

3,787

2,336

View full text Add to dashboard Cite

show abstract

“…HF rates are 40%, 25%, and 50% among TOF, coarctation, and TGA/Fontan-repaired adult survivors, respectively. 98…”

Section: Congenital Cardiovascular Defects and Kawasaki Diseasementioning

confidence: 99%

“…Estimated reoperation rates among adults with TOF, coarctation of the aorta, and TGA and Fontan are 40%, 50%, and 10%, respectively. 98…”

Section: Congenital Cardiovascular Defects and Kawasaki Diseasementioning

confidence: 99%

See 1 more Smart Citation

Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association

Tsao¹,

Aday²,

Almarzooq³

et al. 2023

Circulation

3,530

702

View full text Add to dashboard Cite

BACKGROUND: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). METHODS: The American Heart Association, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing. The 2023 Statistical Update is the product of a full year’s worth of effort in 2022 by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. The American Heart Association strives to further understand and help heal health problems inflicted by structural racism, a public health crisis that can significantly damage physical and mental health and perpetuate disparities in access to health care, education, income, housing, and several other factors vital to healthy lives. This year’s edition includes additional COVID-19 (coronavirus disease 2019) publications, as well as data on the monitoring and benefits of cardiovascular health in the population, with an enhanced focus on health equity across several key domains. RESULTS: Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.

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Switching the Left and the Right Hearts: A Novel Bi-ventricle Mechanical Support Strategy with Spared Native Single-Ventricle

Şişli,

Yıldırım,

Aka

et al. 2023

Ann Biomed Eng

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Mechanical circulatory support (MCS) is used as a bridge-to-heart transplantation for end-stage failing Fontan patients with single-ventricle (SV) circulation. Donor shortage and complexity of the single-ventricle circulation physiology demands novel circulatory support systems and alternative solutions. An out-of-the-box circulation concept in which the left and right ventricles are switched with each other inspired a novel bi-ventricle MCS configuration for the "failing" Fontan patients. In the proposed configuration, the systemic circulation is maintained by a conventional mechanical ventricle assist device while the venous circulation is delegated to the native SV. This approach spares the SV and puts it to a new use at the right-side providing the most needed venous flow pulsatility. To analyze its feasibility and performance, 8 realistic Fontan circulation scenarios have been studied via a multi-compartmental lumped parameter cardiovascular model (LPM). Model is developed specifically for simulating the SV circulation and validated against pulsatile mock-up flow loop measurements for the ideal (Fontan), failed (VD) and assisted Fontan (PVR-cmcs) scenarios. The proposed surgical configuration maintained the cardiac index (3-3.5 l/min/m 2 ) providing a normal mean systemic arterial pressure. For a failed SV with low ejection fraction (EF=26%), representing a typical systemic failure, proposed configuration introduced a venous/pulmonary pulsatility of ~28 mmHg and a drop of 2 mmHg in central venous pressure (CVP) with acceptable pulmonary artery pressures (17.5 mmHg). In the pulmonary vascular resistance (PVR) failure model, it provided approximately 5 mmHg drop in CVP with venous/pulmonary pulsatility reaching ~22 mmHg. For high PVR failure case with a healthy SV (EF = 44%) pulmonary hypertension is likely to occur, indicating a need for precise functional assessment of the failed-ventricle before it is considered for the proposed arrangement.Comprehensive in vitro and in silico results encourage this concept as an economical alternative to the conventional bi-ventricle MCS pending animal experiments.

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Adult Congenital Heart Disease Survivors at Age 50 Years: Medical and Psychosocial Status

Cited by 14 publications

References 18 publications

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association

Switching the Left and the Right Hearts: A Novel Bi-ventricle Mechanical Support Strategy with Spared Native Single-Ventricle

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