Adult Hepatic Mesenchymal Hamartoma: An Unusual Case

Sharma, Monica; Bansal, Preeti; Goyal, Neeraj Krishna

doi:10.4103/0974-2727.141514

Cited by 3 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…MHL in children is primarily localized to the right lobe [8], while in adults, there seems no predilection for a particular lobe, MHL affecting both lobes of liver was seen in almost 22% of cases. In 17 cases (53,1%), gross appearance of mesenchymal hamartoma was cystic, in 9 (28,1 %) cases was solid and in 6 cases (18,.8 %) was both solid and cystic [7] .…”

Section: Discussion:-mentioning

confidence: 97%

“…Only 32 cases of adult mesenchymal hamartoma have been previously reported as individual case reports in the English literature. [7] Of these, 23 (72%) cases have been reported in females and only 9 (28 %) in males with an average age of 40 and 59 years, respectively. in fact, males are more often affected in the pediatric population while females are more often affected in the adult population.…”

Section: Discussion:-mentioning

confidence: 99%

See 1 more Smart Citation

Adult Hepatic Mesenchymal Hamartoma: A Case Report.

Elguazzar¹

2019

IJAR

View full text Add to dashboard Cite

Section: Discussion:-mentioning

confidence: 97%

Section: Discussion:-mentioning

confidence: 99%

Adult Hepatic Mesenchymal Hamartoma: A Case Report.

Elguazzar¹

2019

IJAR

View full text Add to dashboard Cite

Small Bowel Gastrointestinal Stromal Tumor (GIST) Presenting with Liver Abscesses

Rodrigues

Silva²,

Pereira³

2015

J Gastrointest Canc

View full text Add to dashboard Cite

Liver transplantation for a giant mesenchymal hamartoma of the liver in an adult: Case report and review of the literature

Cai

Guo

et al. 2015

WJG

View full text Add to dashboard Cite

Mesenchymal hamartomas of the liver (MHLs) in adults are rare and potentially premalignant lesions, which present as solid/cystic neoplasms. We report a rare case of orthotopic liver transplantation in a patient with a giant MHL. In 2013, a 34-year-old female sought medical advice after a 2-year history of progressive abdominal distention and respiratory distress. Physical examination revealed an extensive mass in the abdomen. Computed tomography (CT) of her abdomen revealed multiple liver cysts, with the diameter of largest cyst being 16 cm × 14 cm. The liver hilar structures were not clearly displayed. The adjacent organs were compressed and displaced. Initial laboratory tests, including biochemical investigations and coagulation profile, were unremarkable. Tumor markers, including levels of AFP, CEA and CA19-9, were within the normal ranges. The patient underwent orthotopic liver transplantation in November 2013, the liver being procured from a 40-year-old man after cardiac death following traumatic brain injury. Warm ischemic time was 7.5 min and cold ischemic time was 3 h. The recipient underwent classical orthotopic liver transplantation. The recipient operative procedure took 8.5 h, the anhepatic phase lasting for 1 h without the use of venovenous bypass. The immunosuppressive regimen included intraoperative induction with basiliximab and high-dose methylprednisolone, and postoperative maintenance with tacrolimus, mycophenolate mofetil, and prednisone. The recipient's diseased liver weighed 21 kg (dry weight) and measured 41 cm × 32 cm × 31 cm. Histopathological examination confirmed the diagnosis of an MHL. The patient did not experience any acute rejection episode or other complication. All the laboratory tests returned to normal within one month after surgery. Three months after transplantation, the immunosuppressive therapy was reduced to tacrolimus monotherapy, and the T-tube was removed after cholangiography showed no abnormalities. Twelve months after transplantation, the patient remains well and is fulfilling all normal activities. Adult giant MHL is extremely rare. Symptoms, physical signs, laboratory results, and radiographic imaging are nonspecific and inconclusive. Surgical excision of the lesion is imperative to make a definite diagnosis and as a cure. Liver transplantation should be considered as an option in the treatment of a non-resectable MHL.

show abstract

Adult Hepatic Mesenchymal Hamartoma: An Unusual Case

Cited by 3 publications

References 8 publications

Adult Hepatic Mesenchymal Hamartoma: A Case Report.

Adult Hepatic Mesenchymal Hamartoma: A Case Report.

Small Bowel Gastrointestinal Stromal Tumor (GIST) Presenting with Liver Abscesses

Liver transplantation for a giant mesenchymal hamartoma of the liver in an adult: Case report and review of the literature

Contact Info

Product

Resources

About