Adult Hippocampal Neurogenesis and Memory

Ortega-Martínez, Sylvia

doi:10.18869/ijabbr.2017.360

Cited by 2 publications

(1 citation statement)

References 62 publications

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“…MDMA causes neuronal damage and memory impairment ( Asi et al, 2011 ; Asl, Saifi, Sakhaie, Zargooshnia, & Mehdizadeh, 2015 ). Given the fundamental role of the hippocampus in learning and memory ( Barzegar et al, 2015 ), it has been speculated that neurogenesis in the hippocampus (newborn granule cells) contribute to memory formation ( Ortega-Martínez, 2017 ).…”

Section: Introductionmentioning

confidence: 99%

The Effects of 3,4-methylenedioxy- methamphetamine on Neurogenesis in the Hippocampus of Male Rats

Asl

Moravej

Kowsari

et al. 2020

Basic Clin. Neurosci. J.

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Introduction: Midkine (MK), a heparin-binding growth factor, is involved in neurological diseases by mediating the inflammatory responses through enhancing the leukocyte migration. The present study assesses the serum concentration of this growth factor among newly multiple sclerosis (MS) and neuromyelitis optica (NMO). Methods: The present research, as a cross-sectional study, which performed at Isfahan University of Medical Sciences. All samples were selected from patients who visited Kashani and Alzahra hospital during two years 2014-2016. The MK level was assessed in 80 new cases of MS, 80 NMO patients and 80 healthy subjects. After collecting blood sera samples, MK serum level was measured using the ELISA. Data were analyzed by SPSS statistical software. Results: The mean of MK level was 1038.58 ± 44.73 pg/ml in MS group, which was significantly higher compared with the mean of MK level in NMO (872.62 ± 55.42 pg/ml) and control groups (605.02 ± 9.42 pg/ml). Conclusion: Overall, these results demonstrated MK plays a prominent role in inflammatory reactions and also in neuroautoimmune diseases, especially in MS. So, the MK level may be applied to earlier diagnosis and also prevention of disease progression by using a special inhibitor.

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Section: Introductionmentioning

confidence: 99%

The Effects of 3,4-methylenedioxy- methamphetamine on Neurogenesis in the Hippocampus of Male Rats

Asl

Moravej

Kowsari

et al. 2020

Basic Clin. Neurosci. J.

View full text Add to dashboard Cite

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From Controversy to Consensus: Neurogenesis and Neuroplasticity

Sirbu,

Ilinoiu,

Vasiliu

et al. 2024

RJMM

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More and more research in recent years has focused on neurogenesis and neuroplasticity. The hippocampus is a key location of adult neurogenesis. Because this part of the brain is regulated by environmental variables, it must be mentioned the therapeutic potential for neurodegenerative illnesses and brain injuries. Furthermore, this information challenges the historical concept of a static brain and tries to demonstrate its flexibility, adaptability, and possibility for regeneration. Those mechanisms which are found in a variety of mammalian species, including humans, are important when it comes to adaptive learning and memory, thus providing insights into cognitive well-being and mental health. The discovery of the brain's dynamic nature represented by new neurons, marks a shift in the field of neurology with far-reaching potentials. This paper highlights the significant potential of adult neurogenesis when it comes to clinical applications such as Alz-heimer’s disease.

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Adult Hippocampal Neurogenesis and Memory

Cited by 2 publications

References 62 publications

The Effects of 3,4-methylenedioxy- methamphetamine on Neurogenesis in the Hippocampus of Male Rats

The Effects of 3,4-methylenedioxy- methamphetamine on Neurogenesis in the Hippocampus of Male Rats

From Controversy to Consensus: Neurogenesis and Neuroplasticity

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