Adult Retroperitoneal Mature Cystic Teratoma Masquerading as Non-Endocrine Primary Adrenal Tumor

Abstract

Teratomas belong to non-seminomatous germ cell tumors and originate from totipotent germ cells. They are mostly made up of tissues derived from all three layers, i.e., endoderm, mesoderm and ectoderm. They can be mature teratomas, which are benign or immature teratomas, having malignant potential. Extra-gonadal mature cystic teratomas are uncommon, particularly in retroperitoneum. Other sites are sacrococcygeal, mediastinal, and pineal regions. They are mostly detected in females in reproductive age group. In this case report, we discuss a female patient being worked up for persistent vomiting and food indigestion, initially managed on the line of acid peptic disease. She was found to have a large retroperitoneal mass in adrenal region producing mass effect on intestines. Later on, it was discovered to be mature cystic teratoma on histopathological evaluation.

Retroperitoneal dermoid cyst complicated with uterine adenomyoma: a case report and literature review

“… 12 – 14 Retroperitoneal dermoid cysts in the abdominal region can also elicit gastrointestinal symptoms, such as indigestion, loss of appetite, nausea, vomiting, and, in cases involving the lower abdomen, constipation and rectal bleeding. 15 , 16 Finally, patients may have neurological symptoms resulting from nerve root compression by large dermoid cysts near vertebral bodies. 17 The clinical presentations of retroperitoneal dermoid cysts thus manifest differently across cases.…”

Extra‐gonadal mature teratoma: A case report of retroperitoneal location with a literature review

“…They are presented in Table 1 . 3 , 4 , 5 , 6 , 7 , 8 The age of patients ranged from 23 to 50 years with an average of 29 years. They were 6 females.…”

“… 1 , 2 They can be mature benign without malignant cells or immature with malignant cells. 3 They commonly occur in the sacrococcygeal region in children and in gonads in adults especially in women. The retroperitoneal localization is not common.…”