Adult Wilms tumour

Zdrojowy, Romuald; Sáwicz-Birkowska, K; Apoznański, Wojciech; Patkowski, Dariusz; Szydełko, Tomasz; Pietras, Wojciech; Dembowski, Janusz

doi:10.1007/s11255-010-9868-7

Cited by 8 publications

(12 citation statements)

References 19 publications

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“…The number of patients with adult WT metastatic to the lung has not yet been reported. A search identified 38 cases of adult WT metastatic to the lungs previously reported in the English literature (Table ) . Of note, Table lists 33 previously reported patients.…”

Section: Discussionmentioning

confidence: 99%

“…The lung is the most common site of metastasis for pediatric WT . Thirty‐eight cases of adult WT metastatic to the lung have been reported to date in the English literature (Table ) . Only two such cases have mentioned the utilization of fine needle aspiration (FNA) biopsy for initial diagnosis of the pulmonary metastasis, one of which does not describe its cytopathologic features in detail .…”

Section: Previously Reported Cases Of Adult Wilms' Tumor Metastatic Tmentioning

confidence: 99%

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Adult wilms' tumor metastatic to the lung: Endobronchial ultrasound‐guided fine needle aspiration biopsy

Perrino

Wang

Chen

et al. 2013

Diagnostic Cytopathology

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Adult Wilms' tumor (WT) is a rare entity with less than 300 cases reported to date in the medical literature. Histologic and cytologic features of adult WT of the kidney are similar to findings in pediatric WT. While the lungs are noted to be the most frequent site of metastatic disease in the pediatric population, the incidence of lung metastases remains unknown for adult WT. A search revealed 38 cases of adult WT with lung metastases published to date in the English literature. Amongst these cases only two have utilized cytology of the lung lesions as a means to arrive at a final diagnosis. We report a case of adult WT metastatic to the lung that was initially diagnosed using endobronchial ultrasound-guided fine needle aspiration biopsy. The aim is to compare the current cytologic and immunohistochemical findings with those cases previously published, to outline the cytologic features of adult WT metastatic to the lung, and to emphasize the significance of cytologic diagnosis in the work-up of adult WT.

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Section: Discussionmentioning

confidence: 99%

Section: Previously Reported Cases Of Adult Wilms' Tumor Metastatic Tmentioning

confidence: 99%

Adult wilms' tumor metastatic to the lung: Endobronchial ultrasound‐guided fine needle aspiration biopsy

Perrino

Wang

Chen

et al. 2013

Diagnostic Cytopathology

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“…Lately, in relapsed AN patients, highdose chemotherapy followed by autologous steam cell rescue has been used as the salvage therapy but only a small number of patients have obtained long complete remission [1,14]. The use of the new combination chemotherapy regimens based on the SIOP-2001 second-line protocol has not improved the outcome in patients with recurrent AN.…”

Section: Naqos Et Al 425mentioning

confidence: 99%

“…Wilms tumor (WT) or nephroblastoma, is one of the most frequent malignant renal tumor in children [1], it is extremely rare in adults, its incidence is 8 per million in children [2], whereas its incidence is lower than 0.2 per million per year in adults, There is no difference between histological features of nephroblastoma in children and in adults, Treatment guidelines for pediatric nephroblastoma are well established but are less clear for adults [1][2][3][4], in view of the rare occurrence of this tumor in adults it is extremely difficult to carry out randomized clinical trials and therapeutic guidelines have not been defined yet.…”

Section: Introductionmentioning

confidence: 99%

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Adult nephroblastoma

Naqos¹,

Bouchbika²,

Taleb³

et al. 2015

IJCRI

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International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations.

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Adult Wilms tumour: A case report

Mounnarath

Zwieky

Aedo-Lopez

et al. 2022

SAGE Open Medical Case Reports

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The Wilms tumour is the fourth most common paediatric malignancy. On the contrary, it is extremely rare in adults as it accounts for less than 1% of all renal malignancies. This scarcity of cases placed a significant challenge in generating evidence-based treatment. Hence, treatment of adult Wilms considerably varies between centres. Standardised guidelines based on international expert consensus for adults have been introduced to help steer management. However, reporting patient outcomes remains limited. In this article, a case study will be presented. This includes modalities of treatment, side effects, tolerability, and outcome. A 40-year-old gentleman with histology consistent with the Wilms tumour received adjuvant chemotherapy according to the UMBRELLA SIOP2016 adult guidelines. Such guidelines were originally adapted from the International Society of Paediatric Oncology protocol. The patient underwent eight cycles of vincristine, actinomycin-D, and doxorubicin and concurrent radiation therapy. Use of the UMBRELLA SIOP2016 adult guideline was shown effective at treating the Wilms tumour in this adult case with minimal severe toxicity. Ongoing follow-up is still needed to determine the long-term effects and prognosis of the patient.

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Adult Wilms tumour

Abstract: Adult patients with Wilms tumour have more aggressive histology and poorer prognosis than children.

Cited by 8 publications

References 19 publications

Adult wilms' tumor metastatic to the lung: Endobronchial ultrasound‐guided fine needle aspiration biopsy

Adult wilms' tumor metastatic to the lung: Endobronchial ultrasound‐guided fine needle aspiration biopsy

Adult nephroblastoma

Adult Wilms tumour: A case report

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