Background: Lung cancer is a type of cancer that begins in the lung. Assessing the level of satisfaction provides actionable insights to improve the healthcare system. Egypt is embarking on a new Universal Health Insurance system (UHIS) to cover all Egyptians by 2032. Aim of the study: The present study aimed to assess lung cancer patient’s satisfaction with universal health Insurance at Port Said Governorate. Design: A descriptive research design was utilized to conduct this study. Sample: A purposive sample used in this study. Sample size: 136 lung cancer patients. Setting: Study conducted at oncology outpatient clinic El Tadamon Specialized Hospital at Port Said Governorate. Tool: An interviewing questionnaire tool divided to two parts, Part1: Consists of A- Socio-demographic characteristics of lung cancer patients, B- Universal health insurance utilization of lung cancer patients, Part II: Patients’ satisfaction adopted tool which contain 7 domains obtained from (Phaswana et al.,2011). Results: The study results revealed that 48.5% of studied lung cancer patients were had moderate level of satisfaction related to their total patient satisfaction. While, 33.8% of them were had high level of satisfaction & 17.7% of studied sample were had low level of satisfaction related their total patient satisfaction.