Advanced algorithms can lead to electrocardiographic misinterpretations

Cardiac resynchronisation therapy response predicts occurrence of atrial fibrillation in non-ischaemic dilated cardiomyopathy

“…Patients were also given a diary in which the information of any medical contacts between their follow‐up visits was to be recorded. The detection of AF relied on electrocardiography, 24 h Holter examination and strips from continuous telemetric control of implanted devices (every 3 to 6 months, when ICDs were systematically checked) (6). AF was defined as an episode, with or without symptoms, lasting at least 10 min (7,8), similar to a large sub‐study of the CARE‐HF trial reported by UC.…”

Atrial fibrillation and microRNAs

“…From a pathophysiological point of view, AF is characterized by atrial electrical remodeling, mainly mediated by ion-channel alterations (Brundel et al, 2001 ; Santulli et al, 2012b ; Xie et al, 2013 ) and structural remodeling (fibrosis and apoptosis), which favors arrhythmia recurrence and maintenance (Perino et al, 2011 ; Santulli and D'Ascia, 2012 ; Santulli et al, 2012b ). A noticeable feature of the electrical remodeling associated with AF is the abbreviation of the effective refractory period favoring reentry (D'Ascia et al, 2010 , 2011 ; Kapur and Macrae, 2013 ), primarily due to shortening of atrial action potential duration (APD).…”