Advanced approaches for improving bioavailability and controlled release of anthocyanins

Shen, Yixiao; Zhang, Ning; Tian, Jinlong; Xin, Guang; Liu, Ling; Sun, Xiyun; B, Li

doi:10.1016/j.jconrel.2021.11.031

Cited by 64 publications

(68 citation statements)

References 147 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 205 ] Further, it is also necessary to protect the drug from being destroyed during the release period and to release the therapeutic agent predictably during the treatment period. [ 206,207 ] The aforementioned reports demonstrate that drugs can be loaded on CDs through various strategies, then released or detached from the CDs in a controlled or stimulated manner. Polymer matrices, hydrogel networks or mesoporous silica are generally adopted as part of CDs‐based controlled release systems, acting to increase local therapeutic effects and minimize side effects (Figure 6d).…”

Section: Applicationsmentioning

confidence: 99%

Carbon Dots in Bioimaging, Biosensing and Therapeutics: A Comprehensive Review

et al. 2022

View full text Add to dashboard Cite

show abstract

Section: Applicationsmentioning

confidence: 99%

Carbon Dots in Bioimaging, Biosensing and Therapeutics: A Comprehensive Review

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Food-grade proteins, especially whey protein, caseinate, gelatin, and soy protein, are attractive in the food industry owing to their health benefits. Their functional properties, including gelation, emulsification, and binding capacity, support their use as alternatives in the development of anthocyanin delivery systems (46,47). In addition, proteins' hydrophobic region can interact with the benzene ring of anthocyanins.…”

Section: Protein-and Polysaccharide-based Encapsulation Protein-based...mentioning

confidence: 99%

Advancement of Protein- and Polysaccharide-Based Biopolymers for Anthocyanin Encapsulation

Song

Chen

et al. 2022

Front. Nutr.

View full text Add to dashboard Cite

Although evidence shows that anthocyanins present promising health benefits, their poor stability still limits their applications in the food industry. Increasing the stability of anthocyanins is necessary to promote their absorption and metabolism and improve their health benefits. Numerous encapsulation approaches have been developed for the targeted release of anthocyanins to retain their bioactivities and ameliorate their unsatisfactory stability. Generally, choosing suitable edible encapsulation materials based on biopolymers is important in achieving the expected goals. This paper presented an ambitious task of summarizing the current understanding and challenges of biopolymer-based anthocyanin encapsulation in detail. The food-grade edible microencapsulation materials, especially for proteins and polysaccharides, should be employed to improve the stability of anthocyanins for effective application in the food industry. The influence factors involved in anthocyanin stability were systematically reviewed and highlighted. Food-grade proteins, especially whey protein, caseinate, gelatin, and soy protein, are attractive in the food industry for encapsulation owing to the improvement of stability and their health benefits. Polysaccharides, such as starch, pectin, chitosan, cellulose, mucilages, and their derivatives, are used as encapsulation materials because of their satisfactory biocompatibility and biodegradability. Moreover, the challenges and perspectives for the application of anthocyanins in food products were presented based on current knowledge. The proposed perspective can provide new insights into the amelioration of anthocyanin bioavailability by edible biopolymer encapsulation.

show abstract

“…Production and demand for supplements containing plant-based bioactive chemicals are steadily increasing, as revealed by several scientific studies that confirm a link between the consumption of products rich in bioactive compounds and the prevention of certain chronic diseases [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Microencapsulation and Bioaccessibility of Phenolic Compounds of Vaccinium Leaf Extracts

et al. 2022

View full text Add to dashboard Cite

In recent years, Vaccinium spp. (bilberry-VMT, lingonberry-VVIT, and blueberry-VCS) have sparked particular interest for their prospective health benefits. The latest investigations have place them as important alternative sources of nutraceuticals as their leaves are the main by-products of berry harvesting. The present study is aimed at investigating the bioaccessibility of phenolic compounds from leaves of the Vaccinium species, both as microencapsulated powder and aqueous extracts, following exposure to in vitro simulated digestion. Moreover, the impact of maltodextrin and glucose microencapsulation carriers on the extracts’ phenolic content was assessed. Prior to encapsulation, the viscosity of the emulsions was shown at a shear stress of 50 s−1 dilatant and a Newtonian behaviour above this value with a final viscosity between 1.024 and 1.049 mPa·s. The final microencapsulation yield for the samples ranged between 79 and 81%. Although the microencapsulated forms presented a targeted release at the intestinal level, the phenolic content decreased after gastrointestinal digestion. The bioaccessibility of the microencapsulated extracts showed higher values than their non-encapsulated counterparts, with the highest value of 45.43% in the VVIT sample, followed by VCS with 41.07%. However, the non-encapsulated VCS sample presented high bioaccessibility after in vitro digestion (38.65%). As concluded, further in vivo research should be conducted on the leaves of the Vaccinium species.

show abstract

Advanced approaches for improving bioavailability and controlled release of anthocyanins

Cited by 64 publications

References 147 publications

Carbon Dots in Bioimaging, Biosensing and Therapeutics: A Comprehensive Review

Carbon Dots in Bioimaging, Biosensing and Therapeutics: A Comprehensive Review

Advancement of Protein- and Polysaccharide-Based Biopolymers for Anthocyanin Encapsulation

Microencapsulation and Bioaccessibility of Phenolic Compounds of Vaccinium Leaf Extracts

Contact Info

Product

Resources

About