The purpose of this paper is to establish ergonomics design procedure and method for FUD, supporting the whole design process and guidance based on the relationship between FUD and anthropometry dimensions. The ergonomics design process of FUD includes: the definition of design features, the definition of body dimensions, design, and evaluation. Computer-Aid Design (CAD) system of FUD ergonomics design includes four subsystems: 3D scanning system, model reconstruction system, product design system, fluid simulation system. Firstly, perineum was scanned with 3D scanning system; Then 3D model was reconstructed in model reconstruction system, and anthropometric data was measured in CATIA; The urination device computer model was designed in CATIA based on 3D human perineum model and its using function; Urine collector model was imported into fluid simulation system for urine fluid simulation when using; then model was optimized based on simulation results; At last, usability and comfort evaluation was conducted with FUD rapid prototyping model. The CAD system for FUD design can be applied in the usability and comfortable design of FUD. The main contributions of this work are given by a method to identify the required design features to guide the FUD design and manufactures in CAD system according perineum virtual models. Index Terms-female urination device, computer-aided design system, model reconstruction, perineum virtual models I.