Advanced CT Techniques for Decreasing Radiation Dose, Reducing Sedation Requirements, and Optimizing Image Quality in Children

Gottumukkala, Ravi V.; Kalra, Mannudeep K.; Tabari, Azadeh; Otrakji, Alexi; Gee, Michael S.

doi:10.1148/rg.2019180082

Cited by 58 publications

(49 citation statements)

References 68 publications

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“…Further approaches for dual energy scanning such as CT systems equipped with photon counting detectors allowing intrinsically for the combination of high resolution and spectral information are evaluated on first prototype systems [49]. The DSCTinherent high-pitch scanning paved the way for fast CT angiographic studies and facilitated a broader acceptance of CT for paediatric examinations because of its potential to avoid sedation [50].…”

Section: Discussionmentioning

confidence: 99%

Principles and applications of dual source CT

Schmidt

Flohr

2020

Physica Medica

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Section: Discussionmentioning

confidence: 99%

Principles and applications of dual source CT

Schmidt

Flohr

2020

Physica Medica

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“…Während die ersten klinischen CT-Scanner durch ihre niedrige räumliche wie zeitliche Auflösung limitiert waren, erreichen die neuesten Geräte eine zeitliche Auflösung von bis zu 66 ms (Gottumukkala et al, 2019). Die…”

Section: Aktuelle Entwicklungen Der Kardiothorakalen Ctaunclassified

Evaluation of ventricular septal defects using high pitch computed tomography angiography of the chest in children with complex congenital heart defects below one year of age

Nau

Wuest

Rompel

et al. 2019

Journal of Cardiovascular Computed Tomography

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“…With a dual‐source CT design, radiologists can examine heart and coronary arteries with much fewer motion artifacts than the single‐source design that has few detector rows 1 . In addition, patients who have trouble holding still on a patient bed, such as children and patients with neurological disorders, are less likely to require anesthesia when being scanned by a dual‐source CT, thereby reducing the exam cost and sedation medical risks 2 …”

Section: Introductionmentioning

confidence: 99%

Physics‐based iterative reconstruction for dual‐source and flying focal spot computed tomography

et al. 2021

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For single-source helical Computed Tomography (CT), both Filtered-Back Projection (FBP) and statistical iterative reconstruction have been investigated. However, for dual-source CT with flying focal spot (DS-FFS CT), a statistical iterative reconstruction that accurately models the scanner geometry and acquisition physics remains unknown to researchers. Therefore, our purpose is to present a novel physics-based iterative reconstruction method for DS-FFS CT and assess its image quality. Methods: Our algorithm uses precise physics models to reconstruct from the native cone-beam geometry and interleaved dual-source helical trajectory of a DS-FFS CT. To do so, we construct a noise physics model to represent data acquisition noise and a prior image model to represent image noise and texture. In addition, we design forward system models to compute the locations of deflected focal spots, the dimension, and sensitivity of voxels and detector units, as well as the length of intersection between x-rays and voxels. The forward system models further represent the coordinated movement between the dual sources by computing their x-ray coverage gaps and overlaps at an arbitrary helical pitch. With the above models, we reconstruct images by an advanced Consensus Equilibrium (CE) numerical method to compute the maximum a posteriori estimate to a joint optimization problem that simultaneously fits all models. Results: We compared our reconstruction with Siemens ADMIRE, which is the clinical standard hybrid iterative reconstruction (IR) method for DS-FFS CT, in terms of spatial resolution, noise profile, and image artifacts through both phantoms and clinical scan datasets. Experiments show that our reconstruction has a higher spatial resolution, with a Task-Based Modulation Transfer Function (MTF task ) consistently higher than the clinical standard hybrid IR. In addition, our reconstruction shows a reduced magnitude of image undersampling artifacts than the clinical standard. Conclusions: By modeling a precise geometry and avoiding data rebinning or interpolation, our physics-based reconstruction achieves a higher spatial resolution and fewer image artifacts with smaller magnitude than the clinical standard hybrid IR.

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Advanced CT Techniques for Decreasing Radiation Dose, Reducing Sedation Requirements, and Optimizing Image Quality in Children

Cited by 58 publications

References 68 publications

Principles and applications of dual source CT

Principles and applications of dual source CT

Evaluation of ventricular septal defects using high pitch computed tomography angiography of the chest in children with complex congenital heart defects below one year of age

Physics‐based iterative reconstruction for dual‐source and flying focal spot computed tomography

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