Advanced drug delivery systems in breast cancer

Singh, Samipta; Singh, Priya; Mishra, Nidhi; Maurya, Priyanka; Singh, Neelu; Nisha, Raquibun; Saraf, Shubhini A.

doi:10.1016/b978-0-323-85503-7.00028-6

Cited by 4 publications

(2 citation statements)

References 185 publications

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“…115,116 Furthermore, the identification of mercury (Hg) in water has been accomplished by the utilization of gold nanoparticles (AuNPs), with documented detection thresholds as minimal as 0.02 parts per billion (ppb). 117 The results mentioned above underscore the remarkable sensitivity of biosensors utilizing gold nanoparticles (AuNPs) in the detection and evaluation of contaminants present in water.…”

Section: Pollution Detectionmentioning

confidence: 99%

Gold Nanoparticles in Nanobiotechnology: From Synthesis to Biosensing Applications

Karnwal,

Kumar Sachan,

Devgon

et al. 2024

ACS Omega

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Nanobiotechnology has ushered in a new era of scientific discovery where the unique properties of nanomaterials, such as gold nanoparticles, have been harnessed for a wide array of applications. This review explores gold nanoparticles' synthesis, properties, and multidisciplinary applications, focusing on their role as biosensors. Gold nanoparticles possess exceptional physicochemical attributes, including size-dependent optical properties, biocompatibility, and ease of functionalization, making them promising candidates for the development of biosensing platforms. The review begins by providing a comprehensive overview of gold nanoparticle synthesis techniques, highlighting the advantages and disadvantages of various approaches. It then delves into the remarkable properties that underpin their success in biosensing, such as localized surface plasmon resonance and enhanced surface area. The discussion also includes the functionalization strategies that enable specific binding to biomolecules, enhancing the sensitivity and selectivity of gold-nanoparticle-based biosensors. Furthermore, this review surveys the diverse applications of gold nanoparticles in biosensing, encompassing diagnostics, environmental monitoring, and drug delivery. The multidisciplinary nature of these applications underscores the versatility and potential of gold nanoparticles in addressing complex challenges in healthcare and environmental science. The review emphasizes the pressing need for further exploration and research in the field of nanobiotechnology, particularly regarding the synthesis, properties, and biosensing applications of gold nanoparticles. With their exceptional physicochemical attributes and versatile functionalities, gold nanoparticles present a promising avenue for addressing complex challenges in healthcare and environmental science, making it imperative to advance our understanding of their synthesis, properties, and applications for enhanced biosensing capabilities and broader scientific innovation.

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Section: Pollution Detectionmentioning

confidence: 99%

Gold Nanoparticles in Nanobiotechnology: From Synthesis to Biosensing Applications

Karnwal,

Kumar Sachan,

Devgon

et al. 2024

ACS Omega

View full text Add to dashboard Cite

show abstract

“…32 Among the studied TDDSs, such as microemulsions, micelles, vesicles, nanoparticles, and transdermal patches, [37][38][39][40][41][42][43] transdermal patches are preferred because of their multi-responsiveness with high water retention capacity, robust mechanical properties, self-healing capacity, adhesiveness, and reusability. [44][45][46][47] Moreover, the utilization of transdermal patches in drug-delivery systems holds promise for enhancing drug penetration and also facilitating a sustained release of therapeutic agents. This approach offers a more straightforward and convenient application method, potentially leading to improved treatment effectiveness and enhanced patient adherence.…”

Section: Introductionmentioning

confidence: 99%