Advanced endoscopic imaging for dysplasia surveillance in ulcerative colitis

Bessissow, Talat; Bisschops, Raf

doi:10.1586/egh.12.65

Cited by 23 publications

(18 citation statements)

References 41 publications

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“…Digital DLC is based on digital post‐processing of the endoscopic images in real time from the video processor instead of narrowing the light by the use of optical filters . Currently, two digital DLC techniques are available, including (i) Fujinon Intelligent Color Enhancement (FICE; Fujifilm, Tokyo, Japan) and (ii) i‐scan (Pentax, Tokyo, Japan).…”

Section: Digital Dlcmentioning

confidence: 99%

Review article: newer optical and digital chromoendoscopy techniques vs. dye‐based chromoendoscopy for diagnosis and surveillance in inflammatory bowel disease

Tontini

Vecchi

Neurath

et al. 2013

Aliment Pharmacol Ther

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SUMMARY BackgroundRecent innovations in gastrointestinal endoscopy have changed our traditional approach to diagnosis and therapy in patients with inflammatory bowel diseases (IBD). While traditionally used dye-based chromoendoscopy (DBC) techniques suffer from several limitations that reduce their utility in daily routine practice, newer 'dye-less' chromoendoscopy (DLC) techniques offer a great potential to overcome most of these limitations.

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Section: Digital Dlcmentioning

confidence: 99%

Review article: newer optical and digital chromoendoscopy techniques vs. dye‐based chromoendoscopy for diagnosis and surveillance in inflammatory bowel disease

Tontini

Vecchi

Neurath

et al. 2013

Aliment Pharmacol Ther

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“…fluorophores) such as collagen, nicotinamide adenine dinucleotide (NAD), flavinor porphyrins, when they are excited with ultraviolet light (<400 nm) or short wavelength light (mostly blue). Autofluorescence is influenced by changes in tissue architecture, the biochemical environment, metabolic status and light absorption properties (determined by haemoglobin concentration) -which occur mainly in neoplasia, inflammation and also ischaemia [15][16][17]. If mucosa or the epithelial layer are thickened autofluorescence is also influenced [18].…”

Section: Autofluorescence Imagingmentioning

confidence: 99%

“…• neovascularization, which induces increased haemoglobin concentration that will absorb the autofluorescence light [15][16][17][18][19][20].…”

Section: Autofluorescence Imagingmentioning

confidence: 99%

Advanced Endoscopic Imaging Techniques for the Study of Colonic Mucosa in Patients with Inflammatory Bowel Disease

Ştefănescu

Pereira

Filip

et al. 2016

Romanian Journal of Internal Medicine

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Background. Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBD) associated with colorectal cancer risk in long-standing diseases. In order to assess the colonic mucosa and to discover dysplastic or neoplastic lesions, advanced endoscopic techniques are needed. Such techniques are detailed in this review: chromoendoscopy, autofluorescence imaging (AFI), narrow band imaging (NBI), i-SCAN, Fujinon Intelligent Color Enhancement (FICE) and confocal laser endomicroscopy (CLE).Aim. The aim of the review is to describe and establish the clinical impact of advanced endoscopic techniques, that could be used in IBD patients'examination in order to assess mucosal healing, microscopic inflammation, dysplasia or neoplasia.Materials and Methods. A literature research about new endoscopic approaches of patients with IBD was made. Results.A lot of studies have been performed to reveal which imaging technique might be used for IBD surveillance. Regarding dysplasia or neoplasia detection and mucosal healing or inflammation assessment, CE proved to be superior to white light endoscopy (WLE), while NBI and AFI did not show an encouraging result. I-SCAN did not improve the colonoscopy quality while FICE has been used in a few studies. CLE could be used to characterize a lesion, providing the same results as conventional histology.Conclusion. At the moment, CE is the only technique which has been included in guidelines for IBD surveillance. CLE can be used to assess any lesion detected with WLE during surveillance, while the other imaging techniques require more studies to determine their efficacy or inefficacy.

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“…However, chromoendoscopy has certain limitations: the mucosa is not always equally sprayed; areas of colourant pooling prevent proper visualization; it has additional cost; and, most importantly, it tends to be more time consuming (39). However, a recent study suggested that chromoendoscopy is both more effective and less costly than WL endoscopy (40).…”

Section: Novel Endoscopic Techniquesmentioning

confidence: 99%

Novel Diagnostic and Therapeutic Techniques for Surveillance of Dysplasia in Patients with Inflammatory Bowel Disease

Iacucci

Uraoka

Gasia

et al. 2014

Canadian Journal of Gastroenterology and Hepatology

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The risk for developing dysplasia and colorectal cancer in patients with longstanding inflammatory bowel disease (IBD) involving the colon is well documented. Random biopsies during white-light, standard-definition colonoscopy (33 to 50 biopsies) with or without dye spraying chromoendoscopy has been the recommended strategy in North America to detect dysplastic lesions in IBD. However, there are several limitations to this approach including poor physician adherence, poor sensitivity, increased procedure time and considerable cost. The new generation of high-definition endoscopes with electronic filter technology provide an opportunity to visualize colonic mucosal and vascular patterns in minute detail, and to identify subtle flat, multifocal, polypoid and pseudopolypoid neoplastic and non-neoplastic lesions. The application of these new technologies in IBD is slowly being adopted in clinical practice. In addition, the advent of confocal laser endomicroscopy provides an opportunity to explore real-time histology, thus redefining the understanding and characterization of the lesions in IBD. There is emerging evidence that serrated adenomas are also associated with longstanding IBD colitis and may be recognized as another important contributing factor to colorectal cancer development. The circumscribed neoplastic lesions can be treated using endoscopic therapeutic management such as mucosal resection or, especially, endoscopic submucosal dissection. This may replace panproctocolectomy in selected patients. The authors review the potential of these techniques to transform endoscopic diagnosis and therapeutic management of dysplasia in IBD.

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Advanced endoscopic imaging for dysplasia surveillance in ulcerative colitis

Cited by 23 publications

References 41 publications

Review article: newer optical and digital chromoendoscopy techniques vs. dye‐based chromoendoscopy for diagnosis and surveillance in inflammatory bowel disease

Review article: newer optical and digital chromoendoscopy techniques vs. dye‐based chromoendoscopy for diagnosis and surveillance in inflammatory bowel disease

Advanced Endoscopic Imaging Techniques for the Study of Colonic Mucosa in Patients with Inflammatory Bowel Disease

Novel Diagnostic and Therapeutic Techniques for Surveillance of Dysplasia in Patients with Inflammatory Bowel Disease

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