Advanced techniques in dobutamine stress echocardiography: focus on myocardial deformation analysis

Joyce, Emer; Delgado, Victoria; Bax, Jeroen J.; Marsan, Nina Ajmone

doi:10.1136/heartjnl-2013-303850

Cited by 11 publications

(5 citation statements)

References 21 publications

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“…Such results mainly differ from our expectations taking into account that patients with DM were significantly older, had more frequently a history of hypertension, significantly more new and/or worsening CAD, especially multivessel disease and greater Syntax score. Although numerous studies highlighted the role of diastolic stress as predictor of CAD presence and its prognosis [ 27 ], [ 28 ], [ 29 ], [ 30 ], [ 31 ] as well in diabetic patients [ 32 ], [ 33 ], [ 34 ], we could not provide such evidence mainly due to small number of patients with DM in our study, lack of performed coronary angiography in all patients, possible good controlled risk factors as well as due to well-known technical factors regarding TDI velocity that can only be measured in one dimension and is significantly limited by angle dependence which produce difficulties in assessment of multiple wall segments (especially apical segments), along with influence of heart motion and contraction of adjacent segments on TDI data during SE, especially during dobutamine application [ 35 ]. Also, we could speculate that the results of our study were in line with those of Fang et al, [ 36 ] who detected the normal response to stress in diabetic patients without a significant difference with a control group that might be due to the early stage of diabetic cardiomyopathy.…”

Section: Discussionmentioning

confidence: 99%

Does the Presence of Diabetes Mellitus Make a Difference in Pharmacological Stress Echocardiography Outcome Results?

Andova¹,

Georgievska-Ismail²,

Srbinovska³

et al. 2018

Open Access Maced J Med Sci

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BACKGROUND:Coronary artery disease (CAD) is the leading cause of mortality and morbidity in patients with diabetes (DM).AIM:The aim of our study was to analyse the ability of pharmacological SE to risk stratify patients with DM using qualitative and quantitative assessment of LV function.METHODS:We prospectively assessed 105 consecutive patients (58.7 ± 9.5 y, 39 male) with known or suspected CAD who underwent dipyridamole or dobutamine SE.RESULTS:Change of systolic LV function at maximal SE was less pronounced in patients with DM, while parameters of the diastolic function and its change with stress were almost insignificant. WMSI in comparison to GLS% didn’t make a difference in SE outcome regarding DM presence. WMSI was almost unchanged at maximal stress in diabetic patients. Conversely, GLS% showed significant worsening at maximal stress in diabetic patients. However, only WMSI at maximal stress along with DM presence appeared as independent predictors of the presence of new and worsening CAD during SE. Longitudinal strain assessed using speckle tracking during pharmacological stress echocardiography was superior to conventional echocardiography expressed by wall motion analysis in making a difference regarding DM presence.CONCLUSION:We confirmed the usefulness of stress echocardiography using qualitative and/or quantitative parameters in the detection of CAD in patients with DM.

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Section: Discussionmentioning

confidence: 99%

Does the Presence of Diabetes Mellitus Make a Difference in Pharmacological Stress Echocardiography Outcome Results?

Andova¹,

Georgievska-Ismail²,

Srbinovska³

et al. 2018

Open Access Maced J Med Sci

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“…Figure 3B and 3C demonstrate the detection of the extent and location of myocardial infarction. During stress echocardiography via exercise or pharmacologic modalities, the angina pectoris can also be evaluated by measuring regional strain in addition to visual assessment of regional wall motion abnormalities [21]. Aside from the diagnosis of ischemic heart disease, it can aid in the decisionmaking process for the revascularization procedures.…”

Section: The Role In Ischemic Heart Diseasementioning

confidence: 99%

Application of Global Longitudinal Strain as a Parameter of Left Ventricular Systolic Function in Echocardiography

Jang

2023

Clin Ultrasound

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Global longitudinal strain (GLS) derived from speckle tracking has emerged as an important tool in assessing myocardial function, offering sensitive insights into cardiac performance. This review highlights GLS as a valuable technique for early detection and monitoring of various cardiac conditions, including heart failure, ischemic heart disease, and valvular heart disease. GLS is a measure of deformation along the longitudinal axis of the heart, providing a quantitative assessment of global left ventricular systolic function. It surpasses traditional parameters like ejection fraction in sensitivity, detecting abnormalities at earlier stages. Additionally, GLS is a robust predictor of adverse events in a wide spectrum of cardiac diseases. While GLS shows promise, it does have some drawbacks like relying on image quality and standardized guidelines. However, its high consistency and lower reliance on the operator make it more reliable in real-world clinical settings. Overall, GLS is an indispensable tool in cardiovascular imaging, empowering clinicians to detect subtle changes in cardiac function, predict adverse events, and optimize patient care and outcomes.

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“…It consists in scanning a patient during a cardiac stress induced by exercise (treadmill or bicycle) or by administration of a pharmacological stressor. The images acquired before and after stress are compared to detect the presence of regions with abnormal wall motion [109]. Dobutamine is a widely available stressor which increases heart rate up to 120-140 beats per minute.…”

Section: Potential Benefits Of High-frame-rate Echocardiographymentioning

confidence: 99%

Introduction to speckle tracking in cardiac ultrasound imaging

2018

Handbook of Speckle Filtering and Tracking in Cardiovascular Ultrasound Imaging and Video

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In this chapter, we will first recall some basic principles of speckle tracking. The fundamentals of speckle tracking in a wider context are essentially described in Chapter 13. We will then treat speckle-tracking echocardiography and echocardiographic particle image velocimetry (echo-PIV) and indicate a number of clinical applications in the context of evaluation of cardiac function. We will then briefly introduce color Doppler approaches complementary to speckle tracking. We will finally present how speckle-tracking techniques could benefit from highframe-rate echocardiography (also called ''ultrafast echocardiography''). We will conclude with the expected contribution of high-frame-rate ultrasound for speckle tracking in three-dimensional (3-D) echocardiography.

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Advanced techniques in dobutamine stress echocardiography: focus on myocardial deformation analysis

Cited by 11 publications

References 21 publications

Does the Presence of Diabetes Mellitus Make a Difference in Pharmacological Stress Echocardiography Outcome Results?

Does the Presence of Diabetes Mellitus Make a Difference in Pharmacological Stress Echocardiography Outcome Results?

Application of Global Longitudinal Strain as a Parameter of Left Ventricular Systolic Function in Echocardiography

Introduction to speckle tracking in cardiac ultrasound imaging

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