Advancement in Research on Aconitum sp. (Ranunculaceae) under Different Area: A Review

Micro‐morphological, environmental and phytochemical investigation of herbal medicines by using LM and SEM: A quality control tool

“…Aconitum heterophyllum has tuberous roots containing alkaloids; benzoylmesaconine, aconitine, hypaconitine, mesaconitine, heteratisine, heterophyllisine, heterophyllidine, heterophylline, atidine, hetidine, hetisinone, isotisine, and benzolylheteratisine (Nyirimigabo et al, 2015;Prasad, Kumar, Patel, Sahu, & Hemalatha, 2012). The aconitum alkaloids mesaconitine and three acetylaconitine have shown antiinflammatory activity (Srivastava, Sharma, Kamal, Dobriyal, & Jadon, 2010;Verma, Ojha, & Raish, 2010). The plant is also administered for treating nervous disorders, digestive system, fever and rheumatism.…”

Analgesic and Antiinflammatory Activity of Genus Aconitum: A Phytochemical and Ethnopharmacological Review

“…Aconitum, commonly known as aconite, monkshood, wolfbane, leopard's bane, Devil's helmet, or blue rocket belongs to the family Ranunculaceae and is widely distributed in the alpine and subalpine regions of the tropical parts of the Northern hemisphere [1,2]. During our study, we observed that several Aconitum species are traditionally used, throughout Asia particularly in China and Japan as an analgesic and for antiinflammatory activity.…”

In vitro evaluation of the pharmacological properties of crude methanol extract and its fractions of Aconitum austrokoreense aerial parts

“…Aconitum austrokoreense Koidz is a perennial herb belonging to the genus Aconitum in the family Ranunculaceae (Luo et al, 2005) and an endemic species with a very limited geographic distribution in the Korean peninsula (Yun et al, 2015). The tuberous roots of genus Aconitum contains are a rich source of alkaloids including alkaloidsbenzoylmecasonine, mesaconitine, aconitine, hypaconitine, heteratisine, heterophyllisine, heterophylline, heterophyllidine, atidine, isotisine, hetidine, and hetsinone andbenzoylheteratisine, which are known to be very toxic (Chan, 2009;Srivastava et al, 2010). However, boiling, decoction or alkaline treatment through deacetylation, debenzoylation, or oxidation reaction hydrolyze aconite alkaloids into less toxic and non-toxic derivatives (Srivastava et al, 2010) such as benzylaconine, and aconine that exhibit some pharmacological activities (Zeng et al, 2016).…”

“…The tuberous roots of genus Aconitum contains are a rich source of alkaloids including alkaloidsbenzoylmecasonine, mesaconitine, aconitine, hypaconitine, heteratisine, heterophyllisine, heterophylline, heterophyllidine, atidine, isotisine, hetidine, and hetsinone andbenzoylheteratisine, which are known to be very toxic (Chan, 2009;Srivastava et al, 2010). However, boiling, decoction or alkaline treatment through deacetylation, debenzoylation, or oxidation reaction hydrolyze aconite alkaloids into less toxic and non-toxic derivatives (Srivastava et al, 2010) such as benzylaconine, and aconine that exhibit some pharmacological activities (Zeng et al, 2016). Therefore, the dried tuberous roots of A. austrokoreense, along with those of other Aconitum species, have been used in traditional herbal medicine to treat various diseases, such as diarrhea, syncope, rheumatic fever, bronchial asthma, painful joints, gastroenteritis, edema, and various tumors (Singhuber et al, 2009).…”