“…However, the discovery of the potent anti-tumor activity of cisplatin, [PtCl 2 (NH 3 ) 2 ] determined the beginning of the modern era of Medicinal inorganic chemistry, accompanied by a huge impact of metal compounds in modern medicine. By exploiting the unique properties of metal ions, Medicinal inorganic chemistry currently offers an attractive option for the rational design of new drugs, looking for defined targets and activities, and new diagnostic and theranostic tools (Zhang and Sadler, 2017;Hanif and Hartinger, 2018;Englinger et al, 2019;Kostelnik and Orvig, 2019;Soldevila-Barreda and Metzler-Nolte, 2019;WahsnerGale et al, 2019;Wang et al, 2019;Anthony et al, 2020;Chamberlain et al, 2020;Chellan and Sadler, 2020;Imberti et al, 2020;Murray and Dyson, 2020;Cirri et al, 2021;Karges and Cohen, 2021;Lin et al, 2021;Silva et al, 2021;Yousuf et al, 2021). In the last decades, the development of metal-based drugs has proven to be a promising approach in the search for new therapeutic tools against parasitic diseases.…”