Advancement of X-ray radiography using microfocus X-ray source in conjunction with amplitude grating and SOI pixel detector, SOPHIAS

Hosono, Ryo; Kawabata, Tomonori; Hayashida, Kentaro; Kudo, Togo; Ozaki, Kyosuke; Teranishi, Nobukazu; Hatsui, Takaki; Hosoi, Takuji; Watanabe, Heiji; Shimura, Takayoshi

doi:10.1364/oe.26.021044

Cited by 4 publications

(2 citation statements)

References 17 publications

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“…Looking into the future, while clinical whole-body CT scanners continually achieve smaller focal spot size and better detector resolution, focal spot size penumbra continues to be a limiting factor in system resolution. For example, the latest photon-counting detectors provide resolutions better than 50 μm (4), while the progress of focal spot size lags behind, reaching 0.4–0.5 mm, currently at low power settings (https://www.itnonline.com/content/canon-medical-systems-aquilion-precision-ct-receives-fda-clearance). Therefore, contact detector inserts (CDIs) should continue to provide an extra boost of resolution in a targeted rescan of a region of interest in future whole-body scanners.…”

Section: Introductionmentioning

confidence: 99%

Regional Ultrahigh-Resolution Rescan in a Clinical Whole-Body CT Scanner Using a Contact Detector Insert

Larsen¹,

Bennett²,

Mazilu³

et al. 2019

Tomography

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Ultrahigh-resolution, low-dose rescans in a region of interest following a general screening computed tomography (CT) scan is motivated by the need to reduce invasive tissue biopsy procedures in cancer screening. We describe a new method to meet the conflicting demands of ultrahigh resolution, high-speed and ultralow-dose, and the first proof-of-concept experiment. With improving detector resolution, the limiting factor for the system resolution of whole-body CT scanners shifts to the penumbra of the source focal spot. The penumbra unsharpness is minimized by inserting flat-panel detector(s) that are in direct contact with the body. In the hybrid system, the detector insert and the CT detector acquire data simultaneously, whereby the standard CT images give the position and orientation of the detector insert(s) as needed for tomosynthesis reconstruction. Imaging tests were performed with a compact photon-counting detector insert on resolution targets of both high- and low-contrast as well as a mouse specimen, all inside a body phantom. Detector insert tomosynthesis provided twice the resolution of the CT scanner alone at the same dose concentration. The short 2-cm beam collimation of the tomosynthesis rescan gave an effective dose equivalent to 6% of an average CT scan in the chest or abdomen.

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Section: Introductionmentioning

confidence: 99%

Regional Ultrahigh-Resolution Rescan in a Clinical Whole-Body CT Scanner Using a Contact Detector Insert

Larsen¹,

Bennett²,

Mazilu³

et al. 2019

Tomography

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show abstract

“…Nevertheless, we believe that this method is suitable for high-energy X-rays that form deep images of objects because the interference effect is not utilized, and the line width of the FZA is wide. In addition, it is possible to visualize the distributions of some materials in an object using a detector with energy resolution 39) and capturing object images using fluorescent X-rays.…”

mentioning

confidence: 99%

Backscattering X-ray imaging using Fresnel zone aperture

Shimura¹,

Hosoi²,

Watanabe³

2021

Appl. Phys. Express

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We demonstrate backscattering X-ray imaging using a Fresnel zone aperture (FZA), where the line width of the outermost circle is 100 μm. The method is a lensless imaging technique employing an optical aperture instead of a lens. We successfully reconstructed test objects from four images observed using a series of FZAs without an iterative procedure during the reconstruction process. We also confirmed the successful reconstruction of a series of images by changing the focal plane in a short computer calculation time, indicating that 3D information can be obtained by measuring a single set of four images.

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Elimination of wraparound artifacts in spatial harmonic imaging using motion blurring

Lim,

Lee,

Lee

et al. 2024

Optics and Lasers in Engineering

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Advancement of X-ray radiography using microfocus X-ray source in conjunction with amplitude grating and SOI pixel detector, SOPHIAS

Cited by 4 publications

References 17 publications

Regional Ultrahigh-Resolution Rescan in a Clinical Whole-Body CT Scanner Using a Contact Detector Insert

Regional Ultrahigh-Resolution Rescan in a Clinical Whole-Body CT Scanner Using a Contact Detector Insert

Backscattering X-ray imaging using Fresnel zone aperture

Elimination of wraparound artifacts in spatial harmonic imaging using motion blurring

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