Advancements in 3D In Vitro Models for Colorectal Cancer
Sara Vitale,
Federica Calapà,
Francesca Colonna
et al.
Abstract:The process of drug discovery and pre‐clinical testing is currently inefficient, expensive, and time‐consuming. Most importantly, the success rate is unsatisfactory, as only a small percentage of tested drugs are made available to oncological patients. This is largely due to the lack of reliable models that accurately predict drug efficacy and safety. Even animal models often fail to replicate human‐specific pathologies and human body's complexity. These factors, along with ethical concerns regarding animal us… Show more
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