Advancements in 3D printing techniques for biomedical applications: a comprehensive review of materials consideration, post processing, applications, and challenges

Ali, Fawad; Kalva, Sumama N.; Koc, Muammer

doi:10.1007/s43939-024-00115-4

Discov Mater

2024

DOI: 10.1007/s43939-024-00115-4

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Advancements in 3D printing techniques for biomedical applications: a comprehensive review of materials consideration, post processing, applications, and challenges

Fawad Ali,

Sumama N. Kalva,

Muammer Koc

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Cited by 2 publications

References 211 publications

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The Future of Bone Repair: Emerging Technologies and Biomaterials in Bone Regeneration

Łuczak,

Palusińska,

Matak

et al. 2024

IJMS

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Bone defects and fractures present significant clinical challenges, particularly in orthopedic and maxillofacial applications. While minor bone defects may be capable of healing naturally, those of a critical size necessitate intervention through the use of implants or grafts. The utilization of traditional methodologies, encompassing autografts and allografts, is constrained by several factors. These include the potential for donor site morbidity, the restricted availability of suitable donors, and the possibility of immune rejection. This has prompted extensive research in the field of bone tissue engineering to develop advanced synthetic and bio-derived materials that can support bone regeneration. The optimal bone substitute must achieve a balance between biocompatibility, bioresorbability, osteoconductivity, and osteoinductivity while simultaneously providing mechanical support during the healing process. Recent innovations include the utilization of three-dimensional printing, nanotechnology, and bioactive coatings to create scaffolds that mimic the structure of natural bone and enhance cell proliferation and differentiation. Notwithstanding the advancements above, challenges remain in optimizing the controlled release of growth factors and adapting materials to various clinical contexts. This review provides a comprehensive overview of the current advancements in bone substitute materials, focusing on their biological mechanisms, design considerations, and clinical applications. It explores the role of emerging technologies, such as additive manufacturing and stem cell-based therapies, in advancing the field. Future research highlights the need for multidisciplinary collaboration and rigorous testing to develop advanced bone graft substitutes, improving outcomes and quality of life for patients with complex defects.

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The Future of Bone Repair: Emerging Technologies and Biomaterials in Bone Regeneration

Łuczak,

Palusińska,

Matak

et al. 2024

IJMS

View full text Add to dashboard Cite

show abstract

Machine Learning in 3D and 4D Printing of Polymer Composites: A Review

Malashin,

Masich,

Tynchenko

et al. 2024

Polymers

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The emergence of 3D and 4D printing has transformed the field of polymer composites, facilitating the fabrication of complex structures. As these manufacturing techniques continue to progress, the integration of machine learning (ML) is widely utilized to enhance aspects of these processes. This includes optimizing material properties, refining process parameters, predicting performance outcomes, and enabling real-time monitoring. This paper aims to provide an overview of the recent applications of ML in the 3D and 4D printing of polymer composites. By highlighting the intersection of these technologies, this paper seeks to identify existing trends and challenges, and outline future directions.

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Advancements in 3D printing techniques for biomedical applications: a comprehensive review of materials consideration, post processing, applications, and challenges

Cited by 2 publications

References 211 publications

The Future of Bone Repair: Emerging Technologies and Biomaterials in Bone Regeneration

The Future of Bone Repair: Emerging Technologies and Biomaterials in Bone Regeneration

Machine Learning in 3D and 4D Printing of Polymer Composites: A Review

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